Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 7/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22576055 | 1.00 | DGAT1 (0.38) | DGAT1MAPTHSP90AA1NPC1PTPN1 | |
| SCHEMBL31366407 | 0.86 | DGAT1 (0.40) | DGAT1MAPTNPC1 | |
| SCHEMBL22576209 | 0.86 | DGAT1 (0.38) | DGAT1MAPTNPC1 | |
| SCHEMBL29717835 | 0.79 | DGAT1 (0.35) | DGAT1MAPTNPC1PTPN1 | |
| SCHEMBL15667286 | 0.79 | DGAT1 (0.35) | DGAT1MAPTNPC1PTPN1 | |
| SCHEMBL24344118 | 0.76 | DGAT1 (0.40) | DGAT1NPC1 | |
| SCHEMBL31277029 | 0.76 | DGAT1 (0.40) | DGAT1NPC1 | |
| SCHEMBL21685421 | 0.76 | DGAT1 (0.38) | DGAT1MAPT | |
| SCHEMBL30467424 | 0.76 | DGAT1 (0.38) | DGAT1MAPT | |
| SCHEMBL23292002 | 0.76 | DGAT1 (0.40) | DGAT1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111699185-B | 6-azaindole compounds | 百时美施贵宝公司 | 2023-06-27 | — | — | CN | disclosed |