Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.36 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | PTGIR | P43119 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30665133 | 0.91 | GPR119 (0.45) | GPR119CYP3A4CHRM3RAB9APTGIR | |
| SCHEMBL30675149 | 0.88 | GPR119 (0.39) | GPR119CYP3A4CHRM3RAB9APTGIR | |
| SCHEMBL12469312 | 0.85 | SLC6A2 (0.46) | CHRM3SLC6A2SLC6A4RAB9ATACR1 | |
| SCHEMBL9900770 | 0.80 | NPC1 (0.40) | GPR119CYP3A4SLC6A2SLC6A4RAB9A | |
| SCHEMBL29017156 | 0.80 | GPR119 (0.38) | GPR119SLC6A2SLC6A4TACR1SLC6A3 | |
| SCHEMBL17560116 | 0.79 | TACR1 (0.41) | CHRM3SLC6A2SLC6A4TACR1SLC6A3 | |
| SCHEMBL28952936 | 0.78 | TACR1 (0.40) | CHRM3SLC6A2SLC6A4RAB9ATACR1 | |
| SCHEMBL27808000 | 0.78 | TACR1 (0.40) | SLC6A2SLC6A4TACR1SLC6A3 | |
| SCHEMBL27884240 | 0.77 | SMN1; SMN2 (0.47) | — | |
| SCHEMBL2348264 | 0.77 | TACR1 (0.42) | SLC6A2SLC6A4TACR1SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111699185-B | 6-azaindole compounds | 百时美施贵宝公司 | 2023-06-27 | — | — | CN | disclosed |