Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 3/20 | 0.39 |
| ▸ | CCR9 | P51686 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.32 |
| ▸ | NMT1 | P30419 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.30 |
| ▸ | HTR3B | O95264 | 1/20 | 0.30 |
| ▸ | HTR3A | P46098 | 1/20 | 0.30 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.30 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26631341 | 1.00 | CYP11B2 (0.39) | CYP11B2CCR9CYP11B1NMT1MEN1 | |
| SCHEMBL26280740 | 0.80 | BACE1 (0.41) | MEN1KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL31347039 | 0.78 | CCR9 (0.34) | CYP11B2CCR9CYP11B1NMT1NPC1 | |
| SCHEMBL748586 | 0.74 | CYP11B2 (0.36) | CYP11B2CCR9 | |
| SCHEMBL29952151 | 0.74 | CYP11B2 (0.36) | CYP11B2CCR9 | |
| SCHEMBL29188992 | 0.73 | CCR9 (0.54) | CYP11B2CCR9RXFP1SMN1; SMN2 | |
| SCHEMBL5364876 | 0.72 | CDK4 (0.43) | CYP11B2CCR9RXFP1HTT | |
| SCHEMBL29643831 | 0.72 | CDC7 (0.44) | CYP11B2CYP11B1MEN1KMT2AHTT | |
| SCHEMBL27424598 | 0.70 | ALOX15 (0.43) | CCR9MEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL25207020 | 0.70 | L3MBTL1 (0.49) | CYP11B2CCR9MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116323557-A | Cyclobutylamide monoacylglycerol lipase modulators | 詹森药业有限公司 | 2023-06-23 | — | — | CN | disclosed |