Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SCD | O00767 | 1/20 | 0.36 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 5/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | RXRB | P28702 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26631356 | 1.00 | HSD11B1 (0.38) | HSD11B1OPRM1MEN1KMT2ASCD | |
| SCHEMBL25412048 | 0.91 | OPRM1 (0.40) | HSD11B1OPRM1MEN1KMT2ASCD | |
| SCHEMBL25424453 | 0.89 | MEN1 (0.40) | HSD11B1OPRM1MEN1KMT2AOPRL1 | |
| SCHEMBL29497407 | 0.86 | SCD5 (0.38) | SCD5TSHR | |
| SCHEMBL29497378 | 0.86 | SCD5 (0.38) | SCD5TSHR | |
| SCHEMBL29469977 | 0.78 | TACR1 (0.43) | MEN1KMT2ASCD5TSHROPRD1 | |
| SCHEMBL30104755 | 0.78 | TACR1 (0.43) | MEN1KMT2ASCD5TSHROPRD1 | |
| SCHEMBL29427116 | 0.78 | TACR1 (0.41) | OPRM1MEN1KMT2ASCD5OPRL1 | |
| SCHEMBL29427157 | 0.78 | TACR1 (0.41) | OPRM1MEN1KMT2ASCD5OPRL1 | |
| SCHEMBL26631402 | 0.78 | TACR1 (0.41) | OPRM1MEN1KMT2ASCD5OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116323557-A | Cyclobutylamide monoacylglycerol lipase modulators | 詹森药业有限公司 | 2023-06-23 | — | — | CN | disclosed |