Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 2/20 | 0.79 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | AGXT | P21549 | 1/20 | 0.44 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.43 |
| ▸ | PRKCI | P41743 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | FLT3 | P36888 | 1/20 | 0.41 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | HCK | P08631 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4009763 | 0.98 | MMP3 (0.82) | MMP3ENPP2KDM4ETDP1MEN1 | |
| SCHEMBL4001097 | 0.98 | MMP3 (0.82) | MMP3ENPP2KDM4ETDP1MEN1 | |
| SCHEMBL338712 | 0.96 | MMP3 (0.73) | MMP3ENPP2KDM4ETDP1MEN1 | |
| SCHEMBL4006124 | 0.95 | MMP3 (0.72) | MMP3ENPP2KDM4ETDP1MEN1 | |
| SCHEMBL694705 | 0.90 | MMP3 (0.67) | MMP3ENPP2KDM4ETDP1MEN1 | |
| SCHEMBL18069859 | 0.89 | MMP3 (0.70) | MMP3ENPP2KDM4ETDP1AGXT | |
| SCHEMBL8338095 | 0.89 | MMP3 (0.70) | MMP3ENPP2KDM4ETDP1PRMT6 | |
| SCHEMBL17873550 | 0.89 | MMP3 (0.70) | MMP3ENPP2KDM4ETDP1BACE1 | |
| SCHEMBL4667163 | 0.89 | MMP3 (1.00) | MMP3ENPP2KDM4ETDP1MEN1 | |
| SCHEMBL237972 | 0.85 | ENPP2 (0.63) | MMP3ENPP2KDM4ETDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116490507-A | Heterocyclic condensation CDC7 kinase inhibitors for the treatment of cancer | 薛定谔公司 | 2023-07-25 | — | — | CN | disclosed |