Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 2/20 | 0.73 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.52 |
| ▸ | AGXT | P21549 | 1/20 | 0.50 |
| ▸ | NAAA | Q02083 | 1/20 | 0.46 |
| ▸ | FLT3 | P36888 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.43 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | CTSS | P25774 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | DHFR | P00374 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30504282 | 0.96 | MMP3 (0.79) | MMP3ENPP2AGXTNAAAFLT3 | |
| SCHEMBL4001097 | 0.94 | MMP3 (0.82) | MMP3ENPP2AGXTNAAAFLT3 | |
| SCHEMBL4009763 | 0.94 | MMP3 (0.82) | MMP3ENPP2AGXTNAAAFLT3 | |
| SCHEMBL4006124 | 0.91 | MMP3 (0.72) | MMP3ENPP2KDM4ETDP1PIK3CA | |
| SCHEMBL694705 | 0.86 | MMP3 (0.67) | MMP3ENPP2AGXTNAAAFLT3 | |
| SCHEMBL8338095 | 0.85 | MMP3 (0.70) | MMP3ENPP2FLT3KDM4ETDP1 | |
| SCHEMBL18069859 | 0.85 | MMP3 (0.70) | MMP3ENPP2AGXTKDM4ETDP1 | |
| SCHEMBL17873550 | 0.85 | MMP3 (0.70) | MMP3ENPP2KDM4ETDP1LMNA | |
| SCHEMBL4667163 | 0.85 | MMP3 (1.00) | MMP3ENPP2KDM4ETDP1PIK3CA | |
| Benzene SCHEMBL5438521 | 0.84 | ENPP2 (0.61) | MMP3ENPP2KDM4ETDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2533783-B1 | COMPOUNDS AND METHODS for the inhibition of HDAC | TEMPERO PHARMACEUTICALS INC (US) | 2015-11-04 | — | — | EP | disclosed |
| EP-2533783-B1 | COMPOUNDS AND METHODS for the inhibition of HDAC | TEMPERO PHARMACEUTICALS INC (US) | 2015-11-04 | — | — | EP | disclosed |
| US-20150038534-A1 | COMPOUNDS AND METHODS | TEMPERO PHARMACEUTICALS, INC. | 2015-02-05 | — | — | US | disclosed |
| US-20150038534-A1 | COMPOUNDS AND METHODS | TEMPERO PHARMACEUTICALS, INC. | 2015-02-05 | — | — | US | disclosed |
| US-20150038534-A1 | COMPOUNDS AND METHODS | TEMPERO PHARMACEUTICALS, INC. | 2015-02-05 | — | — | US | disclosed |
| US-8901156-B2 | Compounds and methods | TEMPERO PHARMACEUTICALS, INC. (US) | 2014-12-02 | — | — | US | disclosed |
| US-8901156-B2 | Compounds and methods | TEMPERO PHARMACEUTICALS, INC. (US) | 2014-12-02 | — | — | US | disclosed |
| US-8901156-B2 | Compounds and methods | TEMPERO PHARMACEUTICALS, INC. (US) | 2014-12-02 | — | — | US | disclosed |
| US-20140294968-A1 | POLYACRYLATE-BASED ACTIVE COMPOUND-COMPRISING PARTICLES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-10-02 | — | — | US | disclosed |
| EP-2736326-A1 | POLYACRYLATE-BASED ACTIVE COMPOUND-COMPRISING PARTICLES | Bayer Intellectual Property GmbH (DE) | 2014-06-04 | — | — | EP | disclosed |
| US-20050275341-A1 | Coumarin compound | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2005-12-15 | — | — | US | disclosed |
| EP-1241943-B1 | USE OF POLYSILOXANES CONTAINING QUATERNARY AMINO GROUPS AS FORMULATION AUXILIARY AGENTS, AND AGENTS CONTAINING THE SAME | BAYER HEALTHCARE AG (DE) | 2005-03-02 | — | — | EP | disclosed |
| WO-2003042148-A2 | PROCESS FOR PRODUCING BISBENZIL COMPOUNDS | SHOWA DENKO K. K. (JP) | 2003-05-22 | — | — | WO | disclosed |
| EP-1241943-A1 | USE OF POLYSILOXANES CONTAINING QUATERNARY AMINO GROUPS AS FORMULATION AUXILIARY AGENTS, AND AGENTS CONTAINING THE SAME | Bayer Aktiengesellschaft (DE) | 2002-09-25 | — | — | EP | disclosed |
| WO-2001035739-A1 | USE OF POLYSILOXANES CONTAINING QUATERNARY AMINO GROUPS AS FORMULATION AUXILIARY AGENTS, AND AGENTS CONTAINING THE SAME | BAYER AKTIENGESELLSCHAFT (DE) | 2001-05-25 | — | — | WO | disclosed |
| CN-1112551-A | Benzovlquinoline derivatives | BAYER AGROCHEM KK (JP) | 1995-11-29 | — | — | CN | disclosed |
| EP-0669320-A2 | Benzoylquinoiline derivatives | NIHON BAYER AGROCHEM K.K. (JP) | 1995-08-30 | — | — | EP | disclosed |
| EP-0160182-B1 | INSECTICIDAL AQUEOUS-BASED MICRO EMULSION COMPOSITIONS | AMERICAN CYANAMID COMPANY (US) | 1993-03-03 | — | — | EP | disclosed |
| US-4904695-A | BLEND WITH SURFACTANT, ANTIFOAM AGENT, THICKENERS, ANTIFREEZE AGENT AND PRESERVATIVE | AMERICAN CYANAMID COMPANY (US) | 1990-02-27 | — | — | US | disclosed |
| EP-0160182-A2 | Insecticidal aqueous-based micro emulsion compositions | AMERICAN CYANAMID COMPANY (US) | 1985-11-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150038534-A1 | COMPOUNDS AND METHODS | XDH, LPXN, CCNY | MMP3 1135/4885ENPP2 558/4885AGXT 27/4885 |
| US-20050275341-A1 | Coumarin compound | XPO1, VKORC1, XPO5 | MMP3 1440/4885ENPP2 4840/4885AGXT 616/4885 |
| US-20140294968-A1 | POLYACRYLATE-BASED ACTIVE COMPOUND-COMPRISING PARTICLES | PLOD3, CUTA, NUP205 | MMP3 1800/4885ENPP2 1570/4885AGXT 570/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.