Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 4-Chlorophenylbiguanide SCHEMBL28036618 | 0.98 | NPC1 (0.52) | NPC1ALDH1A1RAB9AMAPTKDM4E | |
| 4-Chlorophenylbiguanide SCHEMBL3675607 | 0.98 | NPC1 (0.52) | NPC1ALDH1A1RAB9AMAPTKDM4E | |
| 4-Chlorophenylbiguanide SCHEMBL7207570 | 0.94 | NPC1 (0.48) | NPC1ALDH1A1RAB9AMAPTKDM4E | |
| SCHEMBL3068902 | 0.89 | F2 (0.43) | NPC1ALDH1A1RAB9AMAPTTSHR | |
| 4-Chlorophenylbiguanide SCHEMBL3357690 | 0.88 | LMNA (0.48) | NPC1ALDH1A1RAB9AMAPTHTT | |
| SCHEMBL11236184 | 0.87 | NPC1 (0.50) | NPC1ALDH1A1RAB9AMAPTKDM4E | |
| 4-Chlorophenylbiguanide SCHEMBL27542332 | 0.87 | LMNA (0.47) | NPC1ALDH1A1RAB9AMAPTHTT | |
| 4-Chlorophenylbiguanide SCHEMBL28957500 | 0.86 | CYP1A2 (0.49) | NPC1ALDH1A1RAB9AMAPTKDM4E | |
| Hydrochloric Acid SCHEMBL13584911 | 0.85 | NPC1 (0.48) | NPC1ALDH1A1RAB9AMAPTKDM4E | |
| SCHEMBL4113103 | 0.85 | NPC1 (0.66) | NPC1ALDH1A1RAB9AMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1035 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230276794-A1 | MESH MATERIALS FOR CONTROLLED RELEASE OF ANTIVIRALS, METHOD AND USE | 2HEAL INDUSTRIA E COMERCIO DE PRODUTOS QUIMICOS PARA USO INDUSTRIAL LTDA (BR) | 2023-09-07 | — | — | US | claimed |
| EP-4186382-A1 | MESH MATERIALS FOR CONTROLLED RELEASE OF ANTIVIRALS, METHOD AND USE | Universidade Federal de Minas Gerais (BR) | 2023-05-31 | — | — | EP | claimed |
| CN-114437685-B | Degradable dynamic polymer plugging material and preparation method and application thereof | 四川大学 | 2022-12-23 | — | — | CN | claimed |
| CN-114437685-A | Degradable dynamic polymer plugging material and preparation method and application thereof | 四川大学 | 2022-05-06 | — | — | CN | claimed |
| CN-110191637-B | Biomembrane targeting microcapsule carrying non-volatile functional material | 联合利华知识产权控股有限公司 | 2022-01-14 | — | — | CN | claimed |
| CN-107105647-B | Antimicrobial agents for the biocidal of polymers | 维纳泰克斯研究开发生产有限责任公司 | 2021-01-26 | — | — | CN | claimed |
| US-20200277255-A1 | BIGUANIDE COMPOUND AND USE THEREOF | IMMUNOMET THERAPEUTICS INC. | 2020-09-03 | — | — | US | claimed |
| US-20180044283-A1 | BIGUANIDE COMPOUND AND USE THEREOF | IMMUNOMET THERAPEUTICS INC. (US) | 2018-02-15 | — | — | US | claimed |
| EP-3222614-A2 | BIGUANIDE COMPOUND AND USE THEREOF | Immunomet Therapeutics Inc. (US) | 2017-09-27 | — | — | EP | claimed |
| US-20170114008-A1 | NOVEL COMPOUND HAVING IMMUNE DISEASE TREATMENT EFFECT AND USE THEREOF | THE CATHOLIC UNIVERSITY OF KOREA INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) | 2017-04-27 | — | — | US | claimed |
| EP-1684623-A4 | DISPOSABLE CLEANING HEAD | CLOROX CO (US) | 2009-02-18 | — | — | EP | claimed |
| CN-101189971-A | Inorganic/organic nano composite antibacterial agent and its fabric product application | BEIJING CHAMGO NANO TECH CO LT (CN) | 2008-06-04 | — | — | CN | claimed |
| CN-100371027-C | Biological sterilizeld sanitary napkins and functional biological material therefor | ZIANG HUA (CN) | 2008-02-27 | — | — | CN | claimed |
| EP-1684623-A2 | DISPOSABLE CLEANING HEAD | The Clorox Company (US) | 2006-08-02 | — | — | EP | claimed |
| CN-1795977-A | Preparation method for loading functional in organic micromolecules | JIESHIJIE NEW MATERIALS CO LTD (CN) | 2006-07-05 | — | — | CN | claimed |
| CN-1644219-A | Biological sterilizeld sanitary napkins and functional biological material therefor | HUA ZIANG (CN) | 2005-07-27 | — | — | CN | claimed |
| WO-2005032321-A2 | DISPOSABLE CLEANING HEAD | THE CLOROX COMPANY (US) | 2005-04-14 | — | — | WO | claimed |
| US-20050055787-A1 | Disposable cleaning head | THE CLOROX COMPANY | 2005-03-17 | — | — | US | claimed |
| CN-1065453-A | Biguanide derivative, its manufacture method and the Herb of Common violet that contains this derivative | OTSUKA CHEMICAL CO LTD (JP) | 1992-10-21 | — | — | CN | claimed |
| EP-0087049-B1 | CONCENTRATE OF DISINFECTING AGENT | Henkel Kommanditgesellschaft auf Aktien (DE) | 1986-11-12 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180044283-A1 | BIGUANIDE COMPOUND AND USE THEREOF | MKI67, GCG, GCKR | NPC1 3907/4885ALDH1A1 1098/4885RAB9A 763/4885 |
| US-20170114008-A1 | NOVEL COMPOUND HAVING IMMUNE DISEASE TREATMENT EFFECT AND USE THEREOF | NFATC1, CD14, CD209 | NPC1 1585/4885ALDH1A1 2722/4885RAB9A 358/4885 |
| US-20200277255-A1 | BIGUANIDE COMPOUND AND USE THEREOF | MKI67, GCG, GCKR | NPC1 3907/4885ALDH1A1 1098/4885RAB9A 763/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.