4-Chlorophenylbiguanide

4-Chlorophenylbiguanide

SCHEMBL7207570

C1CCCCC1.N=C(N)NC(=N)Nc1ccc(Cl)cc1.N=C(N)NC(=N)Nc1ccc(Cl)cc1

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 4/20 0.48
LMNA P02545 2/20 0.44
ALDH1A1 P00352 7/20 0.42
RAB9A P51151 4/20 0.42
MAPT P10636 4/20 0.42
KDM4E B2RXH2 1/20 0.42
SMN1; SMN2 Q16637 2/20 0.41
NPSR1 Q6W5P4 2/20 0.41
EPHX1 P07099 2/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
HTT P42858 1/20 0.41
PLAU P00749 1/20 0.41
HPN P05981 1/20 0.41
ADRB2 P07550 1/20 0.40
GAA P10253 1/20 0.39
HPGD P15428 1/20 0.39
ALOX15 P16050 1/20 0.39
TSHR P16473 1/20 0.39
HSD17B10 Q99714 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
4-Chlorophenylbiguanide SCHEMBL305068 0.94 NPC1 (0.53) NPC1LMNAALDH1A1RAB9AMAPT
4-Chlorophenylbiguanide SCHEMBL3675607 0.93 NPC1 (0.52) NPC1LMNAALDH1A1RAB9AMAPT
4-Chlorophenylbiguanide SCHEMBL28036618 0.93 NPC1 (0.52) NPC1LMNAALDH1A1RAB9AMAPT
SCHEMBL3068902 0.84 F2 (0.43) NPC1ALDH1A1RAB9AMAPTCYP2C9
4-Chlorophenylbiguanide SCHEMBL3357690 0.83 LMNA (0.48) NPC1LMNAALDH1A1RAB9AMAPT
SCHEMBL11236184 0.82 NPC1 (0.50) NPC1LMNAALDH1A1RAB9AMAPT
4-Chlorophenylbiguanide SCHEMBL27542332 0.82 LMNA (0.47) NPC1LMNAALDH1A1RAB9AMAPT
Phenyl Biguanide SCHEMBL9459112 0.81 ALDH1A1 (0.45) NPC1LMNAALDH1A1RAB9AMAPT
4-Chlorophenylbiguanide SCHEMBL28957500 0.81 CYP1A2 (0.49) NPC1LMNAALDH1A1RAB9AMAPT
Hydrochloric Acid SCHEMBL13584911 0.81 NPC1 (0.48) NPC1LMNAALDH1A1RAB9AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4228589-A1 ANTIPERSPIRANT AND DEODORANT COMPOSITIONS COMPRISING CAPSULES The Procter & Gamble Company (US) 2023-08-23 EP disclosed
WO-2022082187-A1 ANTIPERSPIRANT AND DEODORANT COMPOSITIONS COMPRISING CAPSULES THE PROCTER & GAMBLE COMPANY (US) 2022-04-21 WO disclosed
EP-3568011-A1 BIOFILM TARGETING MICROCAPSULE CARRYING A NON-VOLATILE FUNCTIONAL MATERIAL Unilever PLC (GB) 2019-11-20 EP disclosed
EP-3426223-A1 A ANTIPERSPIRANT COMPOSITION HAVING LONG-LASTING ODOR PROTECTION La Superquimica, S.A. (ES) 2019-01-16 EP disclosed
EP-3370673-A1 ABSORBENT STRUCTURE The Procter and Gamble Company (US) 2018-09-12 EP disclosed
WO-2018130395-A1 BIOFILM TARGETING MICROCAPSULE CARRYING A NON-VOLATILE FUNCTIONAL MATERIAL UNILEVER PLC (GB) 2018-07-19 WO disclosed
WO-2017153468-A1 A ANTIPERSPIRANT COMPOSITION HAVING LONG-LASTING ODOR PROTECTION LA SUPERQUIMICA, S.A. (ES) 2017-09-14 WO disclosed
WO-2017079599-A1 ABSORBENT STRUCTURE THE PROCTER & GAMBLE COMPANY (US) 2017-05-11 WO disclosed
EP-3077129-A1 CLEANING FORMULATION FOR REMOVING RESIDUES ON SURFACES FujiFilm Electronic Materials USA, Inc. (US) 2016-10-12 EP disclosed
WO-2015084921-A1 CLEANING FORMULATION FOR REMOVING RESIDUES ON SURFACES FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. (US) 2015-06-11 WO disclosed
EP-2663339-A1 COMPOSITIONS COMPRISING METALLATED MALODOR CONTROL POLYMERS The Procter and Gamble Company (US) 2013-11-20 EP disclosed
WO-2012097033-A1 COMPOSITIONS COMPRISING METALLATED MALODOR CONTROL POLYMERS THE PROCTER & GAMBLE COMPANY (US) 2012-07-19 WO disclosed
EP-1297101-A2 LAUNDRY SYSTEM HAVING UNITIZED DOSING THE PROCTER & GAMBLE COMPANY (US) 2003-04-02 EP disclosed
EP-1204793-A1 STABLE SILICONE OIL EMULSION COMPOSITION, ARTICLE OF MANUFACTURE, AND METHOD OF FABRIC WRINKLE CONTROL THE PROCTER & GAMBLE COMPANY (US) 2002-05-15 EP disclosed
WO-2001085888-A2 LAUNDRY SYSTEM HAVING UNITIZED DOSING THE PROCTER & GAMBLE COMPANY (US) 2001-11-15 WO disclosed
WO-2001007710-A1 STABLE SILICONE OIL EMULSION COMPOSITION, ARTICLE OF MANUFACTURE, AND METHOD OF FABRIC WRINKLE CONTROL THE PROCTER AND GAMBLE COMPANY (US) 2001-02-01 WO disclosed
EP-0988364-A1 UNCOMPLEXED CYCLODEXTRIN COMPOSITIONS FOR ODOR AND WRINKLE CONTROL THE PROCTER & GAMBLE COMPANY (US) 2000-03-29 EP disclosed
WO-1998056890-A1 UNCOMPLEXED CYCLODEXTRIN COMPOSITIONS FOR ODOR AND WRINKLE CONTROL THE PROCTER & GAMBLE COMPANY (US) 1998-12-17 WO disclosed