Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3581496 | 0.88 | TSHR (0.42) | PAX8ALDH1A1RAB9ANPC1KMT2A | |
| SCHEMBL210860 | 0.87 | DHODH (0.38) | DHODHALDH1A1RAB9AMEN1NPC1 | |
| SCHEMBL28514334 | 0.83 | NPC1 (0.46) | ALDH1A1RAB9ANPC1KMT2AKDM4E | |
| SCHEMBL23662177 | 0.81 | PAX8 (0.39) | PAX8TSHRALOX15 | |
| SCHEMBL28513306 | 0.80 | KDM4E (0.34) | PAX8ALDH1A1KDM4EGAAMAPT | |
| SCHEMBL29389836 | 0.77 | LMNA (0.36) | PAX8ALDH1A1RAB9ACYP2C9LMNA | |
| SCHEMBL14568860 | 0.77 | LCK (0.64) | — | |
| SCHEMBL4797009 | 0.76 | RXFP1 (0.45) | DHODHALDH1A1RAB9AMEN1NPC1 | |
| SCHEMBL3584305 | 0.75 | SCD (0.52) | — | |
| Bromide SCHEMBL6123463 | 0.74 | SMN1; SMN2 (0.44) | DHODHALDH1A1RAB9AMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112010844-B | Preparation method and application of N- (pyrimidine-2-yl) coumarin-7-amine derivative as protein kinase inhibitor | 中国药科大学 | 2023-07-25 | — | — | CN | disclosed |