Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BMPR1B | O00238 | 15/20 | 0.69 |
| ▸ | BMPR1A | P36894 | 15/20 | 0.69 |
| ▸ | TGFBR1 | P36897 | 15/20 | 0.69 |
| ▸ | ACVRL1 | P37023 | 15/20 | 0.69 |
| ▸ | ACVR1 | Q04771 | 15/20 | 0.69 |
| ▸ | TBK1 | Q9UHD2 | 2/20 | 0.42 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.42 |
| ▸ | AXL | P30530 | 1/20 | 0.39 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.39 |
| ▸ | MERTK | Q12866 | 1/20 | 0.39 |
| ▸ | EIF2S1 | P05198 | 1/20 | 0.38 |
| ▸ | EIF2AK3 | Q9NZJ5 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30508351 | 0.89 | BMPR1B (0.70) | BMPR1BBMPR1ATGFBR1ACVRL1ACVR1 | |
| SCHEMBL30508266 | 0.84 | TGFBR1 (0.49) | BMPR1BBMPR1ATGFBR1ACVRL1ACVR1 | |
| SCHEMBL23418645 | 0.83 | BMPR1B (0.86) | BMPR1BBMPR1ATGFBR1ACVRL1ACVR1 | |
| SCHEMBL19806985 | 0.83 | BMPR1B (0.86) | BMPR1BBMPR1ATGFBR1ACVRL1ACVR1 | |
| SCHEMBL20995128 | 0.82 | BMPR1B (1.00) | BMPR1BBMPR1ATGFBR1ACVRL1ACVR1 | |
| SCHEMBL21026974 | 0.82 | BMPR1B (1.00) | BMPR1BBMPR1ATGFBR1ACVRL1ACVR1 | |
| SCHEMBL20995142 | 0.82 | BMPR1B (1.00) | BMPR1BBMPR1ATGFBR1ACVRL1ACVR1 | |
| SCHEMBL22455948 | 0.82 | BMPR1B (0.87) | BMPR1BBMPR1ATGFBR1ACVRL1ACVR1 | |
| SCHEMBL21027214 | 0.82 | BMPR1B (1.00) | BMPR1BBMPR1ATGFBR1ACVRL1ACVR1 | |
| SCHEMBL20995115 | 0.82 | BMPR1B (1.00) | BMPR1BBMPR1ATGFBR1ACVRL1ACVR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116478145-B | ALK2 kinase inhibitors | 杭州邦顺制药有限公司 | 2024-02-02 | — | — | CN | disclosed |
| CN-116478145-A | ALK2 kinase inhibitors | 杭州邦顺制药有限公司 | 2023-07-25 | — | — | CN | disclosed |