Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | BACE1 | P56817 | 2/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | FPR3 | P25089 | 1/20 | 0.39 |
| ▸ | FPR2 | P25090 | 1/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22471455 | 1.00 | GPR119 (0.41) | GPR119TSHRBACE1RORCALOX15 | |
| SCHEMBL3438840 | 0.91 | GPR119 (0.41) | GPR119TSHRBACE1RORCALOX15 | |
| SCHEMBL1785500 | 0.86 | HSD11B1 (0.47) | TSHRALOX15ATMESR2HSD11B1 | |
| SCHEMBL1785499 | 0.86 | HSD11B1 (0.47) | TSHRALOX15ATMESR2HSD11B1 | |
| SCHEMBL327595 | 0.85 | ALDH1A1 (0.46) | GPR119BACE1 | |
| SCHEMBL30107924 | 0.83 | HSD11B1 (0.54) | TSHRALOX15ATMNR1H2HSD11B1 | |
| SCHEMBL1577665 | 0.83 | HSD11B1 (0.54) | TSHRALOX15ATMNR1H2HSD11B1 | |
| SCHEMBL4917650 | 0.79 | HSD11B1 (0.47) | TSHRALOX15ATMESR2HSD11B1 | |
| SCHEMBL31235899 | 0.79 | HTR2C (0.44) | GPR119BACE1RORCFPR3FPR2 | |
| SCHEMBL31758511 | 0.78 | GPR119 (0.44) | GPR119TSHRALOX15ATMUSP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116478145-B | ALK2 kinase inhibitors | 杭州邦顺制药有限公司 | 2024-02-02 | — | — | CN | disclosed |
| CN-116478145-A | ALK2 kinase inhibitors | 杭州邦顺制药有限公司 | 2023-07-25 | — | — | CN | disclosed |