Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 8/20 | 0.45 |
| ▸ | BMPR1B | O00238 | 8/20 | 0.44 |
| ▸ | BMPR1A | P36894 | 8/20 | 0.44 |
| ▸ | TGFBR1 | P36897 | 8/20 | 0.44 |
| ▸ | ACVRL1 | P37023 | 8/20 | 0.44 |
| ▸ | ACVR1 | Q04771 | 8/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | RXRB | P28702 | 1/20 | 0.43 |
| ▸ | RXRG | P48443 | 1/20 | 0.43 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30508250 | 0.94 | WNT1 (0.43) | PIK3CDBMPR1BBMPR1ATGFBR1ACVRL1 | |
| SCHEMBL30508281 | 0.91 | BMPR1B (0.43) | PIK3CDBMPR1BBMPR1ATGFBR1ACVRL1 | |
| SCHEMBL30508271 | 0.91 | BMPR1B (0.43) | PIK3CDBMPR1BBMPR1ATGFBR1ACVRL1 | |
| SCHEMBL30508361 | 0.89 | PIK3CD (0.45) | PIK3CDBMPR1BBMPR1ATGFBR1ACVRL1 | |
| SCHEMBL29152374 | 0.89 | PIK3CD (0.45) | PIK3CDBMPR1BBMPR1ATGFBR1ACVRL1 | |
| SCHEMBL30508187 | 0.84 | GPR119 (0.44) | PIK3CDBMPR1BBMPR1ATGFBR1ACVRL1 | |
| SCHEMBL29042057 | 0.84 | GPR119 (0.44) | PIK3CDBMPR1BBMPR1ATGFBR1ACVRL1 | |
| SCHEMBL30508213 | 0.84 | BMPR1B (0.46) | BMPR1BBMPR1ATGFBR1ACVRL1ACVR1 | |
| SCHEMBL30508174 | 0.84 | BMPR1B (0.63) | BMPR1BBMPR1ATGFBR1ACVRL1ACVR1 | |
| SCHEMBL29041984 | 0.83 | MAPK1 (0.42) | PIK3CDMAPK1RXRARXRBRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116478145-B | ALK2 kinase inhibitors | 杭州邦顺制药有限公司 | 2024-02-02 | — | — | CN | disclosed |
| WO-2023198114-A1 | ALK2 KINASE INHIBITOR | 杭州邦顺制药有限公司 | 2023-10-19 | — | — | WO | disclosed |
| CN-116478145-A | ALK2 kinase inhibitors | 杭州邦顺制药有限公司 | 2023-07-25 | — | — | CN | disclosed |