Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.52 |
| ▸ | TBK1 | Q9UHD2 | 6/20 | 0.50 |
| ▸ | IKBKE | Q14164 | 5/20 | 0.50 |
| ▸ | BMPR1B | O00238 | 5/20 | 0.46 |
| ▸ | BMPR1A | P36894 | 5/20 | 0.46 |
| ▸ | TGFBR1 | P36897 | 5/20 | 0.46 |
| ▸ | ACVRL1 | P37023 | 5/20 | 0.46 |
| ▸ | ACVR1 | Q04771 | 5/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.43 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.42 |
| ▸ | AXL | P30530 | 1/20 | 0.42 |
| ▸ | MERTK | Q12866 | 1/20 | 0.42 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.41 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.41 |
| ▸ | WNT1 | P04628 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29042097 | 1.00 | HDAC3 (0.52) | HDAC3HDAC1HDAC2TBK1IKBKE | |
| SCHEMBL30508285 | 0.89 | HDAC3 (0.55) | HDAC3HDAC1HDAC2TBK1IKBKE | |
| SCHEMBL30508316 | 0.89 | HDAC3 (0.41) | HDAC3HDAC1HDAC2TBK1IKBKE | |
| SCHEMBL29041963 | 0.89 | HDAC3 (0.41) | HDAC3HDAC1HDAC2TBK1IKBKE | |
| SCHEMBL30508377 | 0.83 | BMPR1B (0.61) | HDAC3HDAC1HDAC2TBK1IKBKE | |
| SCHEMBL29041964 | 0.80 | IRAK4 (0.48) | BMPR1BBMPR1ATGFBR1ACVRL1ACVR1 | |
| SCHEMBL30508232 | 0.80 | IRAK4 (0.48) | BMPR1BBMPR1ATGFBR1ACVRL1ACVR1 | |
| SCHEMBL29152375 | 0.79 | BMPR1B (0.64) | TBK1IKBKEBMPR1BBMPR1ATGFBR1 | |
| SCHEMBL30508414 | 0.79 | BMPR1B (0.64) | TBK1IKBKEBMPR1BBMPR1ATGFBR1 | |
| SCHEMBL15681626 | 0.79 | HDAC3 (0.57) | HDAC3HDAC1HDAC2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116478145-B | ALK2 kinase inhibitors | 杭州邦顺制药有限公司 | 2024-02-02 | — | — | CN | disclosed |
| WO-2023198114-A1 | ALK2 KINASE INHIBITOR | 杭州邦顺制药有限公司 | 2023-10-19 | — | — | WO | disclosed |
| CN-116478145-A | ALK2 kinase inhibitors | 杭州邦顺制药有限公司 | 2023-07-25 | — | — | CN | disclosed |