Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.91 |
| ▸ | HPGD | P15428 | 2/20 | 0.91 |
| ▸ | POLB | P06746 | 2/20 | 0.91 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.91 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.91 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.91 |
| ▸ | NPC1 | O15118 | 2/20 | 0.91 |
| ▸ | RAB9A | P51151 | 2/20 | 0.91 |
| ▸ | MEN1 | O00255 | 1/20 | 0.91 |
| ▸ | GMNN | O75496 | 1/20 | 0.91 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.91 |
| ▸ | LMNA | P02545 | 1/20 | 0.91 |
| ▸ | GLA | P06280 | 1/20 | 0.91 |
| ▸ | GAA | P10253 | 1/20 | 0.91 |
| ▸ | APEX1 | P27695 | 1/20 | 0.91 |
| ▸ | BLM | P54132 | 1/20 | 0.91 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.91 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.91 |
| ▸ | ATP2A1 | O14983 | 1/20 | 0.91 |
| ▸ | MTOR | P42345 | 1/20 | 0.91 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17483575 | 0.96 | MAPT (0.92) | MAPTHPGDPOLBMAPK1KMT2A | |
| Thapsigargin SCHEMBL21981207 | 0.95 | MAPT (1.00) | MAPTHPGDPOLBMAPK1KMT2A | |
| Thapsigargin SCHEMBL5690389 | 0.95 | MAPT (1.00) | MAPTHPGDPOLBMAPK1KMT2A | |
| Thapsigargin SCHEMBL21981209 | 0.95 | MAPT (1.00) | MAPTHPGDPOLBMAPK1KMT2A | |
| Thapsigargin SCHEMBL82423 | 0.95 | MAPT (1.00) | MAPTHPGDPOLBMAPK1KMT2A | |
| Thapsigargin SCHEMBL18762159 | 0.95 | MAPT (1.00) | MAPTHPGDPOLBMAPK1KMT2A | |
| Thapsigargin SCHEMBL16491487 | 0.95 | MAPT (1.00) | MAPTHPGDPOLBMAPK1KMT2A | |
| Thapsigargin SCHEMBL18762158 | 0.95 | MAPT (1.00) | MAPTHPGDPOLBMAPK1KMT2A | |
| Thapsigargin SCHEMBL20897006 | 0.94 | MAPT (0.99) | MAPTHPGDPOLBMAPK1KMT2A | |
| SCHEMBL18080775 | 0.94 | MAPT (0.93) | MAPTHPGDPOLBMAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260048156-A1 | FAP-TARGETING PHARMACEUTICAL PRODUCT FOR THERAPY AND DIAGNOSIS OF CANCERS | Atoms for Cure GmbH (DE) | 2026-02-19 | — | — | US | claimed |
| EP-4452326-A1 | FAP-TARGETING PHARMACEUTICAL PRODUCT FOR THERAPY AND DIAGNOSIS OF CANCERS | Atoms for Cure GmbH (DE) | 2024-10-30 | — | — | EP | claimed |
| CN-118541171-A | FAP-targeted pharmaceutical products for cancer treatment and diagnosis | 原子治疗有限公司 | 2024-08-23 | — | — | CN | claimed |
| WO-2023118195-A1 | FAP-TARGETING PHARMACEUTICAL PRODUCT FOR THERAPY AND DIAGNOSIS OF CANCERS | Atoms for Cure GmbH (DE) | 2023-06-29 | — | — | WO | claimed |
| US-20260048156-A1 | FAP-TARGETING PHARMACEUTICAL PRODUCT FOR THERAPY AND DIAGNOSIS OF CANCERS | Atoms for Cure GmbH (DE) | 2026-02-19 | — | — | US | disclosed |
| EP-4452326-A1 | FAP-TARGETING PHARMACEUTICAL PRODUCT FOR THERAPY AND DIAGNOSIS OF CANCERS | Atoms for Cure GmbH (DE) | 2024-10-30 | — | — | EP | disclosed |
| CN-118541171-A | FAP-targeted pharmaceutical products for cancer treatment and diagnosis | 原子治疗有限公司 | 2024-08-23 | — | — | CN | disclosed |
| WO-2023118195-A1 | FAP-TARGETING PHARMACEUTICAL PRODUCT FOR THERAPY AND DIAGNOSIS OF CANCERS | Atoms for Cure GmbH (DE) | 2023-06-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260048156-A1 | FAP-TARGETING PHARMACEUTICAL PRODUCT FOR THERAPY AND DIAGNOSIS OF CANCERS | FAP, ALK, FIBP | MAPT 3883/4885HPGD 4175/4885POLB 3416/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.