Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR132 | Q9UNW8 | 2/20 | 0.50 |
| ▸ | KISS1R | Q969F8 | 3/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.43 |
| ▸ | MME | P08473 | 1/20 | 0.43 |
| ▸ | MMP12 | P39900 | 1/20 | 0.42 |
| ▸ | GNRHR | P30968 | 1/20 | 0.42 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | GNPAT | O15228 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29647938 | 0.92 | GNRHR (0.50) | GPR132KISS1RMMEGNRHROPRM1 | |
| SCHEMBL29413325 | 0.89 | MME (0.49) | GPR132KISS1RHDAC8TBXAS1MME | |
| SCHEMBL29383060 | 0.89 | MME (0.49) | GPR132KISS1RHDAC8TBXAS1MME | |
| SCHEMBL29615239 | 0.88 | GPR132 (0.51) | GPR132KISS1RTBXAS1MMEGNPAT | |
| SCHEMBL29816805 | 0.87 | KISS1R (0.52) | GPR132KISS1RMMEOPRM1OPRD1 | |
| SCHEMBL30038541 | 0.86 | GNRHR (0.50) | GPR132KISS1RMMEGNRHROPRM1 | |
| SCHEMBL29390652 | 0.86 | MME (0.49) | GPR132KISS1RMMEGNRHRCA2 | |
| SCHEMBL21508032 | 0.86 | HDAC8 (0.49) | GPR132HDAC8TBXAS1MMP12KLKB1 | |
| Trifluoroacetic Acid SCHEMBL2367272 | 0.85 | MME (0.46) | GPR132KISS1RTBXAS1MMEKDM4E | |
| SCHEMBL4198783 | 0.84 | GPR132 (0.52) | GPR132TBXAS1MMEKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109929007-B | Preparation method of degarelix key dipeptide intermediate | 连云港恒运药业有限公司 | 2023-07-28 | — | — | CN | disclosed |
| CN-109929012-B | Preparation method of degarelix key tetrapeptide intermediate | 连云港恒运药业有限公司 | 2023-07-28 | — | — | CN | disclosed |