SCHEMBL29647938

SCHEMBL29647938

N[C@H](Cc1ccc2ccccc2c1)C(=O)N[C@H](Cc1ccc(Cl)cc1)C(=O)N[C@H](Cc1cccnc1)C(=O)N[C@@H](CO)C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ GNRHR P30968 9/20 0.50
▸ GPR132 Q9UNW8 1/20 0.48
▸ MME P08473 1/20 0.46
▸ ACE P12821 1/20 0.46
▸ CPA1 P15085 1/20 0.46
▸ ACE2 Q9BYF1 1/20 0.46
▸ OPRD1 P41143 1/20 0.45
▸ ABCB11 O95342 1/20 0.44
▸ KISS1R Q969F8 2/20 0.44
▸ FCER2 P06734 1/20 0.44
▸ DRD1 P21728 1/20 0.43
▸ OPRM1 P35372 1/20 0.43
▸ MRGPRX2 Q96LB1 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29390652 0.96 MME (0.49) GNRHRGPR132MMEACECPA1
SCHEMBL30038541 0.94 GNRHR (0.50) GNRHRGPR132MMEACECPA1
SCHEMBL29374168 0.92 GNRHR (0.49) GNRHRGPR132ABCB11FCER2DRD1
SCHEMBL30509011 0.92 GPR132 (0.50) GNRHRGPR132MMEOPRD1KISS1R
SCHEMBL19620196 0.91 GPR132 (0.47) GNRHRGPR132MMEACECPA1
SCHEMBL29631784 0.88 KISS1R (0.46) GNRHRMMEACECPA1ACE2
SCHEMBL15344724 0.88 GPR132 (0.53) GNRHRGPR132MMEACECPA1
SCHEMBL30552202 0.87 KISS1R (0.47) GNRHRMMEACECPA1ACE2
SCHEMBL31215087 0.87 MME (0.57) MMEACECPA1ACE2OPRD1
SCHEMBL31215105 0.87 MME (0.57) MMEACECPA1ACE2OPRD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220177521-A1 PROCESS FOR THE PREPARATION OF DEGARELIX Fresenius Kabi Ipsum S.R.L. (IT) 2022-06-09 — — US claimed
WO-2025264177-A1 METHOD FOR CLEAVING PROTECTING GROUPS AND ORGANIC COMPOUNDS FROM SUPPORTS POLYPEPTIDE LABORATORIES HOLDING (PPL) AB (SE) 2025-12-26 — — WO disclosed
US-20220177521-A1 PROCESS FOR THE PREPARATION OF DEGARELIX Fresenius Kabi Ipsum S.R.L. (IT) 2022-06-09 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220177521-A1 PROCESS FOR THE PREPARATION OF DEGARELIX VIP, PEPD, SSTR4 GNRHR 42/4885GPR132 2216/4885MME 355/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback