Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.48 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5128246 | 0.91 | HRH3 (0.60) | HRH3MEN1KMT2APRMT5WDR77 | |
| SCHEMBL19266658 | 0.85 | HRH3 (0.54) | HRH3MEN1KMT2APRMT5WDR77 | |
| SCHEMBL5130916 | 0.80 | REV1 (0.65) | HRH3KMT2ANPC1 | |
| SCHEMBL21171660 | 0.79 | FFAR1 (0.55) | HRH3MEN1KMT2APRMT5WDR77 | |
| SCHEMBL3044008 | 0.78 | S1PR5 (0.62) | CHRM4ALOX5 | |
| SCHEMBL5128317 | 0.77 | HRH3 (0.60) | HRH3PRMT5WDR77BCHE | |
| SCHEMBL683554 | 0.76 | RXRA (0.66) | RAB9AALOX5LMNACYP1A2PTGS1 | |
| SCHEMBL2023883 | 0.75 | LMNA (0.58) | RAB9AALOX5LMNACYP1A2PTGS1 | |
| SCHEMBL6376299 | 0.73 | MAOB (0.59) | RAB9AALOX5LMNACYP1A2PTGS1 | |
| SCHEMBL6616547 | 0.73 | LMNA (0.56) | RAB9AALOX5LMNACYP1A2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109384729-B | Pyrimidinedione compounds for cardiac disorders | 迈奥卡迪亚公司 | 2023-06-30 | — | — | CN | disclosed |