SCHEMBL30510360

SCHEMBL30510360

N=C(N)NCCC[C@H](NC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@@H](N)CC(=O)O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCCCC(=O)N[C@@H](CCCCN)C(=O)O

nearest known ligand 0.58

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ C5AR1 P21730 2/20 0.58
▸ PRKACB P22694 1/20 0.53
▸ NPBWR1 P48145 2/20 0.52
▸ CD47 Q08722 1/20 0.52
▸ GLP1R P43220 7/20 0.51
▸ CXCR4 P61073 1/20 0.50
▸ GCGR P47871 1/20 0.50
▸ MC4R P32245 2/20 0.50
▸ IL23R Q5VWK5 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29517075 0.95 C5AR1 (0.54) C5AR1CD47MC4RIL23R
SCHEMBL31140227 0.94 C5AR1 (0.55) C5AR1PRKACBNPBWR1CD47GLP1R
SCHEMBL29540710 0.92 C5AR1 (0.58) C5AR1NPBWR1CD47GLP1RIL23R
SCHEMBL30510367 0.92 MC4R (0.52) C5AR1MC4R
SCHEMBL31140223 0.92 TUBB4A (0.56) C5AR1NPBWR1GLP1RCXCR4IL23R
SCHEMBL29476484 0.91 MC4R (0.50) C5AR1MC4R
SCHEMBL29476447 0.91 MC4R (0.50) C5AR1MC4R
SCHEMBL30878115 0.90 GHSR (0.57) C5AR1
SCHEMBL29419495 0.90 C5AR1 (0.59) C5AR1NPBWR1GLP1RGCGRMC4R
SCHEMBL29973131 0.89 C5AR1 (0.55) C5AR1CD47GLP1RGCGRIL23R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260085092-A1 MELANOCORTIN RECEPTOR LIGANDS IPSEN PHARMA SAS (FR) 2026-03-26 — — US disclosed
CN-120152725-A Methods of treating obesity using MC4R agonists 节奏制药公司 2025-06-13 — — CN disclosed
CN-119119190-A Melanocortin receptor ligands 益普生制药股份有限公司 2024-12-13 — — CN disclosed
CN-105837661-B Melanocortin receptor ligands 益普生制药股份有限公司 2024-10-15 — — CN disclosed
CN-116507353-A Methods of treating melanocortin-4 receptor pathway-related disorders 节奏制药公司 2023-07-28 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260085092-A1 MELANOCORTIN RECEPTOR LIGANDS THRB, MC1R, MC5R C5AR1 1092/4885PRKACB 1262/4885NPBWR1 29/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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