SCHEMBL30510409

SCHEMBL30510409

O=C(O)[C@H]1COCCN1C(=O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.44

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
FABP5 Q01469 3/20 0.44
FABP7 O15540 2/20 0.44
FKBP1A P62942 1/20 0.41
KMT2A Q03164 3/20 0.40
TSHR P16473 1/20 0.39
EPHX2 P34913 1/20 0.38
CD274 Q9NZQ7 2/20 0.38
OPRD1 P41143 1/20 0.38
ALDH1A1 P00352 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
MEN1 O00255 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
POLB P06746 1/20 0.36
PREP P48147 1/20 0.36
TMEM97 Q5BJF2 1/20 0.36
SIGMAR1 Q99720 1/20 0.36
PDCD1 Q15116 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30510389 1.00 FABP5 (0.44) FABP5FABP7FKBP1AKMT2ATSHR
SCHEMBL17596685 1.00 FABP5 (0.44) FABP5FABP7FKBP1AKMT2ATSHR
SCHEMBL15285020 1.00 FABP5 (0.44) FABP5FABP7FKBP1AKMT2ATSHR
SCHEMBL15285015 1.00 FABP5 (0.44) FABP5FABP7FKBP1AKMT2ATSHR
SCHEMBL30510381 1.00 FABP5 (0.44) FABP5FABP7FKBP1AKMT2ATSHR
SCHEMBL30812377 0.93 FABP5 (0.43) FABP5FABP7FKBP1AKMT2ATSHR
SCHEMBL28885273 0.89 KMT2A (0.39) FABP5FABP7KMT2ATSHREPHX2
SCHEMBL119409 0.88 FABP5 (0.46) FABP5FABP7FKBP1AKMT2AEPHX2
SCHEMBL15353000 0.87 FABP5 (0.41) FABP5FABP7KMT2ATSHREPHX2
SCHEMBL30485106 0.87 FABP5 (0.41) FABP5FABP7KMT2ATSHREPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250090699-A1 FAP TARGETING CYCLIC PEPTIDES AND CONJUGATES THEREOF NOVARTIS AG (CH) 2025-03-20 US disclosed
US-20240148821-A1 PHARMACEUTICAL USE OF CYCLIC PEPTIDE COMPOUND CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2024-05-09 US disclosed
EP-4316503-A1 PHARMACEUTICAL USE OF CYCLIC PEPTIDE COMPOUND CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2024-02-07 EP disclosed
US-20230151060-A1 CYCLIC PEPTIDE COMPOUND HAVING KRAS INHIBITORY ACTION CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2023-05-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230151060-A1 CYCLIC PEPTIDE COMPOUND HAVING KRAS INHIBITORY ACTION KRAS, NRAS, HRAS FABP5 4094/4885FABP7 4602/4885FKBP1A 1152/4885
US-20250090699-A1 FAP TARGETING CYCLIC PEPTIDES AND CONJUGATES THEREOF FAP, FIBP, FGF23 FABP5 383/4885FABP7 610/4885FKBP1A 1006/4885
US-20240148821-A1 PHARMACEUTICAL USE OF CYCLIC PEPTIDE COMPOUND VIP, IAPP, KRAS FABP5 4026/4885FABP7 4376/4885FKBP1A 1185/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.