Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUT | P33316 | 2/20 | 0.37 |
| ▸ | SDCBP | O00560 | 2/20 | 0.36 |
| ▸ | SDC2 | P34741 | 2/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.36 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.36 |
| ▸ | PRF1 | P14222 | 2/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 2/20 | 0.34 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.32 |
| ▸ | ITGAV | P06756 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29264667 | 0.91 | MAPK1 (0.38) | DUTALDH1A1HDAC6KDM4EALOX15 | |
| SCHEMBL20786955 | 0.88 | AOC3 (0.40) | PRMT5WDR77SRD5A1 | |
| SCHEMBL2145293 | 0.86 | KDM4E (0.40) | DUTPRF1ALDH1A1F10KDM4E | |
| SCHEMBL2144245 | 0.82 | ACHE (0.40) | DUTPRF1ALDH1A1MAPK1 | |
| SCHEMBL31597793 | 0.81 | DRD2 (0.37) | DUT | |
| SCHEMBL30434602 | 0.81 | PARP1 (0.45) | SDCBPSDC2PRMT5WDR77BRD4 | |
| SCHEMBL2144299 | 0.81 | PARP1 (0.45) | SDCBPSDC2PRMT5WDR77BRD4 | |
| SCHEMBL28608040 | 0.79 | PRMT5 (0.39) | SDCBPSDC2PRMT5WDR77PRF1 | |
| SCHEMBL2145361 | 0.79 | KDM4E (0.50) | DUTALDH1A1KDM4EALOX15TSHR | |
| SCHEMBL31597728 | 0.77 | MAP3K5 (0.40) | DUTPRMT5WDR77ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023138612-A1 | HETEROCYCLIC COMPOUNDS USEFUL AS HPK1 INHIBITORS | SILEXON AI TECHNOLOGY CO., LTD. (CN) | 2023-07-27 | — | — | WO | disclosed |