Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 4/20 | 0.38 |
| ▸ | DUT | P33316 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TNF | P01375 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.34 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | ADAM17 | P78536 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30512969 | 0.91 | DUT (0.37) | MAPK1DUTALDH1A1KDM4EHDAC6 | |
| SCHEMBL31597793 | 0.88 | DRD2 (0.37) | DUTTYMS | |
| SCHEMBL2145361 | 0.86 | KDM4E (0.50) | MAPK1DUTALDH1A1KDM4EHPGD | |
| SCHEMBL18765812 | 0.83 | MAPK1 (0.46) | MAPK1ALDH1A1KDM4EHPGDTNF | |
| SCHEMBL2144629 | 0.82 | ACHE (0.40) | MAPK1DUTALDH1A1GABRA1GABRG2 | |
| SCHEMBL20786955 | 0.81 | AOC3 (0.40) | — | |
| SCHEMBL18765603 | 0.81 | PARP1 (0.45) | MAPK1ALDH1A1KDM4EHPGDTNF | |
| SCHEMBL31597728 | 0.80 | MAP3K5 (0.40) | DUTALDH1A1 | |
| SCHEMBL2145293 | 0.79 | KDM4E (0.40) | MAPK1DUTALDH1A1KDM4EHPGD | |
| SCHEMBL18765788 | 0.77 | MAPK1 (0.50) | MAPK1ALDH1A1KDM4EHPGDTNF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118019735-A | Arylsulfonyl compounds as CCR6 inhibitors | 坎莫森特里克斯公司 | 2024-05-10 | — | — | CN | disclosed |