SCHEMBL30514616

SCHEMBL30514616

CCc1ccccc1Nc1ccc(NC(C)CC)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.58
CYP3A4 P08684 3/20 0.58
ALOX15 P16050 3/20 0.58
TSHR P16473 3/20 0.58
HSD17B10 Q99714 3/20 0.58
SMN1; SMN2 Q16637 3/20 0.58
HIF1A Q16665 2/20 0.58
THRB P10828 2/20 0.58
TDP1 Q9NUW8 2/20 0.58
L3MBTL1 Q9Y468 2/20 0.58
TP53 P04637 1/20 0.58
HSP90AA1 P07900 1/20 0.58
CASP1 P29466 1/20 0.58
ALOX12 P18054 2/20 0.46
MAPK1 P28482 1/20 0.46
POLB P06746 2/20 0.43
LMNA P02545 1/20 0.41
RECQL P46063 1/20 0.41
ATM Q13315 1/20 0.41
GAA P10253 3/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14320839 0.84 HTT (0.50) ALDH1A1SMN1; SMN2TDP1POLBGAA
SCHEMBL11791407 0.83 ALDH1A1 (0.40) ALDH1A1CYP3A4ALOX15TSHRHSD17B10
SCHEMBL11799941 0.83 ALDH1A1 (0.40) ALDH1A1CYP3A4ALOX15TSHRHSD17B10
SCHEMBL30514612 0.82 ALDH1A1 (0.60) ALDH1A1CYP3A4ALOX15TSHRHSD17B10
SCHEMBL93902 0.79 ALDH1A1 (0.72) ALDH1A1CYP3A4ALOX15TSHRHSD17B10
SCHEMBL3148744 0.79 MEN1 (0.48) ALDH1A1SMN1; SMN2POLBGAAMAPT
SCHEMBL29657744 0.79 MAPT (0.50) ALDH1A1CYP3A4ALOX15TSHRHSD17B10
SCHEMBL6029657 0.79 MAPT (0.50) ALDH1A1CYP3A4ALOX15TSHRHSD17B10
SCHEMBL9874686 0.78 ALDH1A1 (0.86) ALDH1A1CYP3A4ALOX15TSHRHSD17B10
SCHEMBL6673568 0.78 ALDH1A1 (0.57) ALDH1A1CYP3A4ALOX15TSHRHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116589369-A Rubber anti-aging agent and preparation method thereof 圣奥化学科技有限公司 2023-08-15 CN disclosed