Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.41 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14320839 | 0.94 | HTT (0.50) | MEN1KMT2AHTTALDH1A1SMN1; SMN2 | |
| SCHEMBL29657744 | 0.88 | MAPT (0.50) | MEN1KMT2AALDH1A1SMN1; SMN2GAA | |
| SCHEMBL6029657 | 0.88 | MAPT (0.50) | MEN1KMT2AALDH1A1SMN1; SMN2GAA | |
| SCHEMBL887264 | 0.86 | NPC1 (0.59) | MEN1KMT2AHTTALDH1A1SMN1; SMN2 | |
| SCHEMBL30146895 | 0.86 | NPC1 (0.59) | MEN1KMT2AHTTALDH1A1SMN1; SMN2 | |
| SCHEMBL23846636 | 0.85 | HTT (0.44) | MEN1KMT2AHTTALDH1A1SMN1; SMN2 | |
| SCHEMBL11347170 | 0.85 | MAPT (0.58) | MEN1KMT2AHTTALDH1A1SMN1; SMN2 | |
| SCHEMBL20351918 | 0.85 | HTT (0.64) | MEN1KMT2AHTTALDH1A1SMN1; SMN2 | |
| SCHEMBL31310663 | 0.85 | POLB (0.47) | MEN1KMT2AHTTALDH1A1SMN1; SMN2 | |
| SCHEMBL3142020 | 0.85 | ADRA2B (0.40) | MEN1KMT2AALDH1A1SMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7642028-B2 | surface layers are a polymeric composition including a resin and a cyclic polymers such as polyethylene terephthalate, acrylic acid-ethylene copolymer, styrene-co-maleic anhydride copolymer; polyhexamethylene adipamide etc. and cyclic poly(bisphenol A carbonate), cyclic poly(bisphenol C carbonate) etc. | XEROX CORPORATION (US) | 2010-01-05 | — | — | US | claimed |
| US-20060210894-A1 | Imaging members | XEROX CORPORATION | 2006-09-21 | — | — | US | claimed |