SCHEMBL6029657

SCHEMBL6029657

CCc1ccccc1Nc1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.50
GAA P10253 4/20 0.50
KDM4E B2RXH2 3/20 0.50
MEN1 O00255 3/20 0.50
KMT2A Q03164 3/20 0.50
TDP1 Q9NUW8 2/20 0.50
GLA P06280 1/20 0.50
RECQL P46063 1/20 0.50
ALDH1A1 P00352 6/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
RAB9A P51151 2/20 0.49
KCNK3 O14649 1/20 0.49
KCNK9 Q9NPC2 1/20 0.49
LMNA P02545 1/20 0.48
CYP1A2 P05177 1/20 0.48
CYP2D6 P10635 1/20 0.48
CYP2C9 P11712 1/20 0.48
CYP2C19 P33261 1/20 0.48
CLCN2 P51788 1/20 0.47
ALOX15 P16050 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29657744 1.00 MAPT (0.50) MAPTGAAKDM4EMEN1KMT2A
SCHEMBL14320839 0.93 HTT (0.50) MAPTGAAKDM4EMEN1KMT2A
SCHEMBL3148744 0.88 MEN1 (0.48) MAPTGAAKDM4EMEN1KMT2A
SCHEMBL1548694 0.86 ALDH1A1 (0.54) MAPTGAAKDM4EMEN1KMT2A
SCHEMBL30146895 0.86 NPC1 (0.59) MAPTGAAMEN1KMT2ATDP1
SCHEMBL887264 0.86 NPC1 (0.59) MAPTGAAMEN1KMT2ATDP1
SCHEMBL4544859 0.85 KCNH3 (0.51) MAPTGAAKDM4EMEN1KMT2A
SCHEMBL23846636 0.84 HTT (0.44) MAPTGAAKDM4EMEN1KMT2A
SCHEMBL11347170 0.84 MAPT (0.58) MAPTGAAKDM4EMEN1KMT2A
SCHEMBL22640385 0.84 MAPT (0.48) MAPTGAAKDM4EMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3464317-B1 AMINOSTEROID DERIVATIVES AND PROCESS FOR PRODUCING SAME UNIV LAVAL (CA) 2023-04-26 EP disclosed
US-20210126198-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND MONOAMINE COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2021-04-29 US disclosed
US-10290815-B2 Composition, compound, material for organic electroluminescence element, ink composition, organic electroluminescence element, and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2019-05-14 US disclosed
US-9705091-B2 Aromatic heterocycle derivative and organic electroluminescent element using same IDEMITSU KOSAN CO., LTD. (JP) 2017-07-11 US disclosed
EP-2585216-A1 COMPLEXES Johnson Matthey PLC (GB) 2013-05-01 EP disclosed
WO-2011161451-A1 COMPLEXES JOHNSON MATTHEY PLC (GB) 2011-12-29 WO disclosed
WO-2009048541-A2 COMPOUNDS AND METHODS FOR USE IN TREATING NEOPLASIA AND CANCER PURDUE RESEARCH FOUNDATION (US) 2009-04-16 WO disclosed
US-6986886-B2 Hair conditioning compositions and their use in hair coloring compositions THE PROCTER & GAMBLE COMPANY (US) 2006-01-17 US disclosed
US-20040158941-A1 Hair colouring and conditioning compositions THE PROCTER & GAMBLE COMPANY (US) 2004-08-19 US disclosed
US-20040158938-A1 Method for colouring hair THE PROCTER & GAMBLE COMPANY 2004-08-19 US disclosed
CN-86103619-A The preparation method of the bicyclic pyrazolidinones that 7-replaces 1986-10-29 CN disclosed
EP-0020138-B1 N-(2-AMINO-3-ETHYL-ALPHA-METHYLBENZYLIDENE)-2,6-DIETHYLANILINE AND ITS PREPARATION; ANTIOXIDANT ADDITIVE MIXTURES INCLUDING SAID COMPOUND; THE USE OF SAID COMPOUND, SAID ADDITIVE MIXTURES AND CERTAIN ALKYLATED ANILINES AS ANTIOXIDANTS FOR ORGANIC MATERIALS; AND ORGANIC MATERIALS AFFORDED ANTIOXIDANT PROTECTION AS AFORESAID ETHYL CORPORATION (US) 1983-06-22 EP disclosed
US-4269720-A N-(2-AMINO-3-ETHYL-ALPHA-METHYLBENZYLIDENE)-2,6-DIETHYL ANILINE ETHYL CORPORATION (US) 1981-05-26 US disclosed
EP-0020138-A2 N-(2-amino-3-ethyl-alpha-methylbenzylidene)-2,6-diethylaniline and its preparation; antioxidant additive mixtures including said compound; the use of said compound, said additive mixtures and certain alkylated anilines as antioxidants for organic materials; and organic materials afforded antioxidant protection as aforesaid ETHYL CORPORATION (US) 1980-12-10 EP disclosed
US-4172081-A Benzotriazole ultraviolet stabilizers EASTMAN KODAK COMPANY (US) 1979-10-23 US disclosed
US-4123474-A STABILIZED THERMOPLASTIC MOLDING MATERIAL GENERAL ELECTRIC COMPANY (US) 1978-10-31 US disclosed
US-4116929-A POLYESTERS EASTMAN KODAK COMPANY (US) 1978-09-26 US disclosed
US-4088734-A WASHING GASES WITH AQUEOUS ALKALINE SOLUTION OF ZINC OR LEAD COMPOUND AND/OR ANTHRAQUINONE SULFONIC ACID INSTITUT FRANCAIS DU PETROLE (FR) 1978-05-09 US disclosed
US-4017508-A POLYMERS EASTMAN KODAK COMPANY (US) 1977-04-12 US disclosed
US-3957424-A Enzyme-activated oxidative process for coloring hair THE PROCTER & GAMBLE COMPANY (US) 1976-05-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10290815-B2 Composition, compound, material for organic electroluminescence element, ink composition, organic electroluminescence element, and electronic device EED, BMI1, CD99 MAPT 1057/4885GAA 3187/4885KDM4E 225/4885
US-20210126198-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND MONOAMINE COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE SLC18A1, SLC18A2, SLC18A3 MAPT 704/4885GAA 514/4885KDM4E 1043/4885
US-20040158941-A1 Hair colouring and conditioning compositions FNIP1, CUTA, SHH MAPT 2803/4885GAA 4604/4885KDM4E 4131/4885
US-20040158938-A1 Method for colouring hair COX5B, SHH, DNMT3A MAPT 3941/4885GAA 4055/4885KDM4E 515/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.