Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC25A1 | P53007 | 1/20 | 0.64 |
| ▸ | POLB | P06746 | 7/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | CASP6 | P55212 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ACLY | P53396 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30515745 | 1.00 | SLC25A1 (0.64) | SLC25A1POLBMEN1KMT2AGPR55 | |
| SCHEMBL30252330 | 0.78 | SLC25A1 (1.00) | SLC25A1POLBMEN1KMT2AHSD17B10 | |
| SCHEMBL17329296 | 0.78 | SLC25A1 (1.00) | SLC25A1POLBMEN1KMT2AHSD17B10 | |
| SCHEMBL11172199 | 0.70 | POLB (0.77) | SLC25A1POLBMEN1KMT2AGPR55 | |
| SCHEMBL11026357 | 0.66 | POLB (0.65) | SLC25A1POLBMEN1KMT2AHSD17B10 | |
| SCHEMBL3554085 | 0.66 | MAPK1 (0.85) | POLBMEN1KMT2AGPR55HSD17B10 | |
| SCHEMBL10422318 | 0.66 | SLC25A1 (0.66) | SLC25A1POLBMEN1KMT2AMAPK1 | |
| SCHEMBL8067660 | 0.64 | POLB (0.62) | SLC25A1POLBMEN1KMT2AHSD17B10 | |
| SCHEMBL25413760 | 0.64 | KMT2A (0.50) | SLC25A1POLBMEN1KMT2AHSD17B10 | |
| SCHEMBL3555375 | 0.64 | MAPK1 (0.68) | SLC25A1POLBMEN1KMT2AGPR55 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4181911-A1 | THE ROLE OF PMCIC IN THE TUMOR MICROENVIRONMENT | Universitätsklinikum Regensburg (DE) | 2023-05-24 | — | — | EP | claimed |
| EP-4181911-A1 | THE ROLE OF PMCIC IN THE TUMOR MICROENVIRONMENT | Universitätsklinikum Regensburg (DE) | 2023-05-24 | — | — | EP | disclosed |