Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC25A1 | P53007 | 1/20 | 0.66 |
| ▸ | CA12 | O43570 | 1/20 | 0.61 |
| ▸ | CA2 | P00918 | 1/20 | 0.61 |
| ▸ | CA9 | Q16790 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.56 |
| ▸ | NHERF1 | O14745 | 1/20 | 0.56 |
| ▸ | CRHBP | P24387 | 1/20 | 0.56 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL95345 | 0.86 | ALDH1A1 (0.56) | SLC25A1CA12CA2CA9MAPT | |
| SCHEMBL11407805 | 0.84 | CA2 (0.63) | SLC25A1CA12CA2CA9MAPT | |
| SCHEMBL8820451 | 0.83 | CA2 (0.61) | SLC25A1CA12CA2CA9MAPT | |
| SCHEMBL7572373 | 0.83 | L3MBTL1 (0.67) | CA12CA2CA9MAPTALDH1A1 | |
| SCHEMBL23832738 | 0.83 | CA12 (0.61) | SLC25A1CA12CA2CA9MAPT | |
| SCHEMBL9635088 | 0.82 | ALDH1A1 (0.53) | SLC25A1CA2MAPTALDH1A1POLB | |
| SCHEMBL9749290 | 0.82 | CRHBP (0.61) | SLC25A1CA12CA2CA9MAPT | |
| SCHEMBL7443125 | 0.82 | SLC25A1 (0.68) | SLC25A1CA12CA2CA9MAPT | |
| SCHEMBL7015594 | 0.81 | GUSB (0.66) | SLC25A1CA12CA2CA9MAPT | |
| SCHEMBL2741009 | 0.81 | CA2 (0.58) | SLC25A1CA12CA2CA9MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0356382-A2 | Multilayer plaster | CIBA-GEIGY AG (CH) | 1990-02-28 | — | — | EP | claimed |
| EP-0255020-B1 | WATER SOLUBLE TRIPHENODIOXAZINE COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS DYESTUFFS | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-09-19 | — | — | EP | disclosed |
| EP-0356382-A2 | Multilayer plaster | CIBA-GEIGY AG (CH) | 1990-02-28 | — | — | EP | disclosed |
| US-4895954-A | Dyeing wool, cellulose | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-01-23 | — | — | US | disclosed |
| US-4816574-A | FIBER-REACTIVE DYES FOR WOOL, CELLULOSE | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-03-28 | — | — | US | disclosed |