SCHEMBL17329296

SCHEMBL17329296

O=C(O)c1ccc(Cl)c(S(=O)(=O)Nc2cccc([N+](=O)[O-])c2)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC25A1 P53007 1/20 1.00
MEN1 O00255 7/20 0.65
KMT2A Q03164 7/20 0.65
MAPT P10636 6/20 0.63
POLB P06746 4/20 0.63
ALDH1A1 P00352 3/20 0.60
CASP3 P42574 1/20 0.59
SENP8 Q96LD8 1/20 0.59
SENP7 Q9BQF6 1/20 0.59
SENP6 Q9GZR1 1/20 0.59
HSD17B10 Q99714 1/20 0.58
WDR5 P61964 2/20 0.55
KDM4E B2RXH2 1/20 0.55
TDP1 Q9NUW8 1/20 0.55
L3MBTL1 Q9Y468 1/20 0.55
LMNA P02545 2/20 0.54
SMN1; SMN2 Q16637 1/20 0.54
MAPK1 P28482 1/20 0.54
GAA P10253 1/20 0.53
NPC1 O15118 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30252330 1.00 SLC25A1 (1.00) SLC25A1MEN1KMT2AMAPTPOLB
SCHEMBL11172199 0.82 POLB (0.77) SLC25A1MEN1KMT2AMAPTPOLB
SCHEMBL7443125 0.81 SLC25A1 (0.68) SLC25A1MEN1KMT2AMAPTPOLB
SCHEMBL10422318 0.80 SLC25A1 (0.66) SLC25A1MEN1KMT2AMAPTPOLB
SCHEMBL30515744 0.78 SLC25A1 (0.64) SLC25A1MEN1KMT2AMAPTPOLB
SCHEMBL30515745 0.78 SLC25A1 (0.64) SLC25A1MEN1KMT2AMAPTPOLB
SCHEMBL8366106 0.78 CASP3 (0.81) SLC25A1MEN1KMT2AMAPTPOLB
SCHEMBL30515750 0.78 MAPK1 (0.73) SLC25A1MEN1KMT2APOLBALDH1A1
SCHEMBL11772392 0.78 SLC25A1 (0.64) SLC25A1MEN1KMT2AMAPTPOLB
SCHEMBL27179628 0.78 MAPT (0.84) SLC25A1MEN1KMT2AMAPTPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4181911-A1 THE ROLE OF PMCIC IN THE TUMOR MICROENVIRONMENT Universitätsklinikum Regensburg (DE) 2023-05-24 EP claimed
WO-2022013295-A1 THE ROLE OF PMCIC IN THE TUMOR MICROENVIRONMENT UNIVERSITÄTSKLINIKUM REGENSBURG (DE) 2022-01-20 WO claimed
US-20180028647-A1 MODIFICATIONS OF THERAPEUTIC AGENTS FOR ENHANCED DELIVERY TO TARGET SITES CLARIA ODIN LLC 2018-02-01 US claimed
US-20170349949-A1 METHODS OF SELECTING SUBJECTS FOR TREATMENT WITH METABOLIC MODULATORS CLARIA PARTIKULA LLC 2017-12-07 US claimed
US-12133720-B2 Methods and compositions for restoring homeostatic capacity of a subject Palo Alto Investors LP (US) 2024-11-05 US disclosed
US-20240358783-A1 METHOD AND SYSTEM FOR THE TRANSDERMAL ADMINISTRATION OF A PSYCHEDELIC AGENT LCT TECHNOLOGIES LLC 2024-10-31 US disclosed
EP-4313007-A1 TRANSDERMAL SYSTEM, FORMULATION, AND METHOD FOR THE THERAPEUTIC ADMINISTRATION OF A PSYCHEDELIC AGENT Lyfe CHNG, LLC (US) 2024-02-07 EP disclosed
EP-4181911-A1 THE ROLE OF PMCIC IN THE TUMOR MICROENVIRONMENT Universitätsklinikum Regensburg (DE) 2023-05-24 EP disclosed
US-20230026731-A1 TRANSDERMAL SYSTEM, FORMULATION, AND METHOD FOR THE THERAPEUTIC ADMINISTRATION OF A PSYCHEDELIC AGENT LCT TECHNOLOGIES LLC 2023-01-26 US disclosed
WO-2022221072-A1 TRANSDERMAL SYSTEM, FORMULATION, AND METHOD FOR THE THERAPEUTIC ADMINISTRATION OF A PSYCHEDELIC AGENT MYCRODOSE THERAPEUTICS INC. (US) 2022-10-20 WO disclosed
US-20220323389-A1 TREATING NON-ALCOHOLIC FATTY LIVER DISEASE AND INFLAMMATORY STEATOHEPATITIS WITH SLC25A1 INHIBITORS GEORGETOWN UNIVERSITY (US) 2022-10-13 US disclosed
WO-2022212789-A1 TRANSDERMAL SYSTEM, FORMULATION, AND METHOD FOR THE THERAPEUTIC ADMINISTRATION OF A PSYCHEDELIC AGENT MYCRODOSE THERAPEUTICS INC. (US) 2022-10-06 WO disclosed
US-20210076956-A1 Methods and Compositions for Restoring Homeostatic Capacity of a Subject Palo Alto Investors LP 2021-03-18 US disclosed
US-10835134-B2 Methods and compositions for restoring homeostatic capacity of a subject PALO ALTO INVESTORS (US) 2020-11-17 US disclosed
US-10478492-B2 Modifications of therapeutic agents for enhanced delivery to target sites CLARIA PARTIKULA LLC (US) 2019-11-19 US disclosed
US-10006005-B2 Culture medium and method for inducing differentiation of pluripotent stem cells to hepatoblasts NATIONAL UNIVERSITY CORPORATION CHIBA UNIVERSITY (JP) 2018-06-26 US disclosed
US-20180028647-A1 MODIFICATIONS OF THERAPEUTIC AGENTS FOR ENHANCED DELIVERY TO TARGET SITES CLARIA ODIN LLC 2018-02-01 US disclosed
US-20170349949-A1 METHODS OF SELECTING SUBJECTS FOR TREATMENT WITH METABOLIC MODULATORS CLARIA PARTIKULA LLC 2017-12-07 US disclosed
US-20160053230-A1 Culture Medium And Method For Inducing Differentiation of Pluripotent Stem Cells To Hepatoblasts NATIONAL UNIVERSITY CORPORATION CHIBA UNIVERSITY (JP) 2016-02-25 US disclosed
US-20150359888-A1 Methods and Compositions for Restoring Homeostatic Capacity of a Subject PALO ALTO INVESTORS 2015-12-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230026731-A1 TRANSDERMAL SYSTEM, FORMULATION, AND METHOD FOR THE THERAPEUTIC ADMINISTRATION OF A PSYCHEDELIC AGENT HTR7, HTR6, PNMT SLC25A1 1861/4885MEN1 1233/4885KMT2A 789/4885
US-20240358783-A1 METHOD AND SYSTEM FOR THE TRANSDERMAL ADMINISTRATION OF A PSYCHEDELIC AGENT HTR7, HTR6, PNMT SLC25A1 2070/4885MEN1 1350/4885KMT2A 896/4885
US-20180028647-A1 MODIFICATIONS OF THERAPEUTIC AGENTS FOR ENHANCED DELIVERY TO TARGET SITES PDK1, PC, PDK2 SLC25A1 79/4885MEN1 1378/4885KMT2A 1257/4885
US-10478492-B2 Modifications of therapeutic agents for enhanced delivery to target sites PDK1, PC, PDK2 SLC25A1 79/4885MEN1 1378/4885KMT2A 1257/4885
US-20220323389-A1 TREATING NON-ALCOHOLIC FATTY LIVER DISEASE AND INFLAMMATORY STEATOHEPATITIS WITH SLC25A1 INHIBITORS SLC10A1, SLC27A1, SLC25A3 SLC25A1 16/4885MEN1 4426/4885KMT2A 2418/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.