Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 9/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 8/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29045114 | 1.00 | HDAC6 (0.56) | HDAC6HDAC1HDAC3HDAC2SLC6A3 | |
| SCHEMBL2224785 | 0.84 | P2RX7 (0.49) | SLC6A3KCNH2TAAR1TRPV1 | |
| SCHEMBL3550941 | 0.84 | BAZ2B (0.51) | HDAC6HDAC2SLC6A3KCNH2TAAR1 | |
| Hydrochloric Acid SCHEMBL28637532 | 0.83 | P2RX7 (0.47) | SLC6A3KCNH2TAAR1TRPV1 | |
| SCHEMBL29827745 | 0.82 | P4HTM (0.60) | KCNH2TRPV1 | |
| SCHEMBL22387735 | 0.82 | HDAC6 (0.61) | HDAC6HDAC1HDAC3HDAC2HDAC8 | |
| SCHEMBL13701813 | 0.81 | LMNA (0.46) | SLC6A3KCNH2TAAR1TRPV1 | |
| SCHEMBL6140597 | 0.81 | TRPV4 (0.52) | SLC6A3KCNH2TAAR1HDAC4TRPV1 | |
| SCHEMBL3544820 | 0.80 | PTPN1 (0.47) | SLC6A3KCNH2TAAR1TRPV1 | |
| SCHEMBL22915155 | 0.80 | HSP90AA1 (0.49) | HDAC6HDAC4TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116514790-A | Tri-aromatic heterocyclic piperazine small molecular organic compound targeting STAT3 and application thereof | 华东师范大学 | 2023-08-01 | — | — | CN | disclosed |