Sugi Predict

Sugi Predict / Compounds / Venorphin

Venorphin

Venorphin

SCHEMBL30516272

CC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(N)=O

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ OPRM1 P35372 10/20 0.67
▸ OPRK1 P41145 10/20 0.67
▸ KISS1R Q969F8 5/20 0.65
▸ IL23R Q5VWK5 1/20 0.63
▸ CXCR4 P61073 3/20 0.62
▸ NPBWR1 P48145 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Venorphin SCHEMBL29489924 0.92 NPBWR1 (0.65) OPRM1OPRK1KISS1RNPBWR1
SCHEMBL16636399 0.92 KISS1R (0.73) OPRM1OPRK1KISS1RIL23R
SCHEMBL14479443 0.91 KISS1R (0.74) KISS1RIL23RCXCR4
SCHEMBL11199735 0.90 CXCR4 (0.59) OPRM1OPRK1KISS1RCXCR4
SCHEMBL31105513 0.90 IL23R (0.66) OPRM1OPRK1KISS1RIL23R
SCHEMBL31238557 0.89 KISS1R (0.63) OPRM1OPRK1KISS1RCXCR4
SCHEMBL31105433 0.89 IL23R (0.69) IL23RCXCR4NPBWR1
SCHEMBL30608444 0.88 KISS1R (0.61) OPRM1OPRK1KISS1RCXCR4
SCHEMBL31273381 0.88 KISS1R (0.61) OPRM1OPRK1KISS1RCXCR4
SCHEMBL31105545 0.87 NPBWR1 (0.69) KISS1RIL23RNPBWR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250134812-A1 SYNTHETIC GLYCOLIPIDS AND GLYCOLIPOSOME COMPOSITIONS : SUITABLE FOR CARGO DELIVERY TO THE CENTRAL NERVOUS SYSTEM KORANEX CAPITAL (CA) 2025-05-01 — — US claimed
WO-2023141693-A1 SYNTHETIC GLYCOLIPIDS AND GLYCOLIPOSOME COMPOSITIONS SUITABLE FOR CARGO DELIVERY TO THE CENTRAL NERVOUS SYSTEM KORANEX CAPITAL (CA) 2023-08-03 — — WO claimed
WO-2023141692-A1 SYNTHETIC GLYCOLIPIDS AND GLYCOLIPOSOME COMPOSITIONS SUITABLE FOR CARGO DELIVERY TO THE CENTRAL NERVOUS SYSTEM KORANEX CAPITAL (CA) 2023-08-03 — — WO claimed
US-20250134812-A1 SYNTHETIC GLYCOLIPIDS AND GLYCOLIPOSOME COMPOSITIONS : SUITABLE FOR CARGO DELIVERY TO THE CENTRAL NERVOUS SYSTEM KORANEX CAPITAL (CA) 2025-05-01 — — US disclosed
WO-2023141693-A1 SYNTHETIC GLYCOLIPIDS AND GLYCOLIPOSOME COMPOSITIONS SUITABLE FOR CARGO DELIVERY TO THE CENTRAL NERVOUS SYSTEM KORANEX CAPITAL (CA) 2023-08-03 — — WO disclosed
WO-2023141692-A1 SYNTHETIC GLYCOLIPIDS AND GLYCOLIPOSOME COMPOSITIONS SUITABLE FOR CARGO DELIVERY TO THE CENTRAL NERVOUS SYSTEM KORANEX CAPITAL (CA) 2023-08-03 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250134812-A1 SYNTHETIC GLYCOLIPIDS AND GLYCOLIPOSOME COMPOSITIONS : SUITABLE FOR CARGO DELIVERY TO THE CENTRAL NERVOUS SYSTEM SGMS2, SGMS1, GBA2 OPRM1 639/4885OPRK1 2064/4885KISS1R 3261/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.