Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.41 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29008215 | 0.94 | CHEK1 (0.44) | TSHRALDH1A1ATMNPSR1RAB9A | |
| SCHEMBL3453563 | 0.88 | NPC1 (0.48) | TSHRALDH1A1ATMNPSR1RAB9A | |
| SCHEMBL2965416 | 0.88 | TSHR (0.55) | TSHRALDH1A1ATMNPSR1RAB9A | |
| SCHEMBL15202657 | 0.82 | — | — | |
| SCHEMBL7127913 | 0.80 | AKR1B1 (0.42) | TSHRCHEK1SRD5A2PDK2 | |
| SCHEMBL2310400 | 0.77 | TSHR (0.42) | TSHRALDH1A1ATMNPSR1RAB9A | |
| SCHEMBL14034508 | 0.76 | TSHR (0.41) | TSHRALDH1A1ATMNPSR1RAB9A | |
| SCHEMBL7153161 | 0.75 | ALDH1A1 (0.52) | TSHRALDH1A1ATMNPSR1RAB9A | |
| SCHEMBL3531737 | 0.73 | GAA (0.45) | TSHRALDH1A1ATMNPSR1RAB9A | |
| SCHEMBL3047696 | 0.73 | PGR (0.48) | TSHRALDH1A1ATMNPSR1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8338078-B2 | Photoresist undercoat-forming material and patterning process | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2012-12-25 | — | — | US | disclosed |
| US-20100104977-A1 | PHOTORESIST UNDERCOAT-FORMING MATERIAL AND PATTERNING PROCESS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2010-04-29 | — | — | US | disclosed |