SCHEMBL7153161

SCHEMBL7153161

C=CCc1ccc2c(c1)Cc1ccc(CC=C)cc1-2

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.52
GABRA1 P14867 5/20 0.52
GABRB2 P47870 5/20 0.52
MAPT P10636 5/20 0.52
CNR2 P34972 5/20 0.52
MEN1 O00255 2/20 0.52
GAA P10253 2/20 0.52
CNR1 P21554 2/20 0.52
KMT2A Q03164 2/20 0.52
PPARG P37231 2/20 0.52
PPARD Q03181 2/20 0.52
NPSR1 Q6W5P4 2/20 0.52
KDM4E B2RXH2 2/20 0.52
HPGD P15428 2/20 0.52
ALDH2 P05091 1/20 0.52
AKR1B1 P15121 1/20 0.52
XDH P47989 1/20 0.44
TNKS O95271 1/20 0.44
PARP1 P09874 1/20 0.44
CYP3A4 P08684 3/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3961022 0.94 GABRA1 (0.57) ALDH1A1GABRA1GABRB2MAPTCNR2
SCHEMBL10374502 0.89 ALDH1A1 (0.51) ALDH1A1GABRA1GABRB2MAPTCNR2
SCHEMBL23527433 0.84 ALDH1A1 (0.46) ALDH1A1GABRA1GABRB2MAPTCNR2
SCHEMBL23527421 0.80 MAOA (0.55) ALDH1A1GABRA1GABRB2MAPTCNR2
SCHEMBL629048 0.77 ALDH1A1 (0.40) ALDH1A1GABRA1GABRB2MAPTCNR2
SCHEMBL10494619 0.75 XDH (0.48) ALDH1A1GABRA1GABRB2MAPTCNR2
SCHEMBL3051643 0.75 TSHR (0.42) ALDH1A1MAPTGAANPSR1KDM4E
SCHEMBL10828054 0.74 ALDH1A1 (0.43) ALDH1A1GABRA1GABRB2MAPTCNR2
SCHEMBL24650531 0.73 XDH (0.47) ALDH1A1GABRA1GABRB2MAPTCNR2
SCHEMBL9715080 0.73 TSHR (0.53) ALDH1A1MAPTNPSR1KDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040087761-A1 Novel polycarbazole and process for preparation thereof NARA INSTITUTE OF SCIENCE AND TECHNOLOGY (JP) 2004-05-06 US disclosed