Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 1/20 | 0.54 |
| ▸ | QPCT | Q16769 | 1/20 | 0.53 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.53 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.51 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.51 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | PTGES | O14684 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | CYP11B1 | P15538 | 6/20 | 0.49 |
| ▸ | CYP11B2 | P19099 | 6/20 | 0.49 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.49 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.49 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.49 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.49 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30832786 | 0.90 | PDE3B (0.65) | FGFR1QPCTQPCTLPDE3BPDE3A | |
| SCHEMBL1884345 | 0.90 | PDE3B (0.65) | FGFR1QPCTQPCTLPDE3BPDE3A | |
| SCHEMBL7270901 | 0.79 | CYP11B1 (0.52) | FGFR1CYP1A2CYP3A4CYP2C9PTGES | |
| SCHEMBL7273923 | 0.79 | AURKA (0.56) | FGFR1CYP3A4CYP2C9PTGESCYP2C19 | |
| SCHEMBL31441275 | 0.78 | PRMT5 (0.52) | FGFR1QPCTQPCTLPDE3BPDE3A | |
| SCHEMBL17067225 | 0.78 | FGFR1 (0.59) | FGFR1QPCTQPCTLPDE3BPDE3A | |
| SCHEMBL16284624 | 0.77 | TLR8 (0.59) | FGFR1QPCTQPCTLCYP1A2CYP3A4 | |
| SCHEMBL4287824 | 0.76 | CYP11B2 (0.57) | FGFR1PDE3BPDE3ACYP11B1CYP11B2 | |
| SCHEMBL30494348 | 0.76 | PDE3B (0.70) | FGFR1QPCTQPCTLPDE3BPDE3A | |
| SCHEMBL6909727 | 0.76 | PDE3B (0.68) | FGFR1QPCTQPCTLPDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116528867-A | Compounds for the treatment of Alzheimer's disease | 艾伯塔大学理事会 | 2023-08-01 | — | — | CN | disclosed |