Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 7/20 | 0.52 |
| ▸ | CYP11B2 | P19099 | 7/20 | 0.52 |
| ▸ | MMP2 | P08253 | 1/20 | 0.52 |
| ▸ | MMP13 | P45452 | 1/20 | 0.52 |
| ▸ | MMP14 | P50281 | 1/20 | 0.52 |
| ▸ | CYP19A1 | P11511 | 7/20 | 0.49 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | CLK2 | P49760 | 1/20 | 0.45 |
| ▸ | CLK3 | P49761 | 1/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.45 |
| ▸ | PGR | P06401 | 1/20 | 0.45 |
| ▸ | PTGES | O14684 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7273923 | 0.83 | AURKA (0.56) | CYP11B1CYP11B2MMP2MMP13MMP14 | |
| SCHEMBL30516503 | 0.79 | FGFR1 (0.54) | CYP11B1CYP11B2CYP19A1CYP17A1FGFR1 | |
| Hydrochloric Acid SCHEMBL7273927 | 0.79 | MMP2 (0.54) | CYP11B1CYP11B2MMP2MMP13MMP14 | |
| SCHEMBL7270988 | 0.79 | RAB9A (0.49) | CYP11B1CYP11B2MMP2MMP13MMP14 | |
| SCHEMBL4287824 | 0.78 | CYP11B2 (0.57) | CYP11B1CYP11B2MMP2MMP13MMP14 | |
| SCHEMBL31317820 | 0.78 | CYP19A1 (0.71) | CYP11B1CYP11B2MMP2MMP13MMP14 | |
| SCHEMBL21812408 | 0.78 | CYP19A1 (0.71) | CYP11B1CYP11B2MMP2MMP13MMP14 | |
| Hydrochloric Acid SCHEMBL7264278 | 0.77 | CYP11B2 (0.55) | CYP11B1CYP11B2MMP2MMP13MMP14 | |
| SCHEMBL27671973 | 0.76 | NR4A2 (0.61) | CYP11B1CYP11B2MMP2MMP13MMP14 | |
| SCHEMBL31475468 | 0.76 | DAO (0.65) | KDM4EHPGDHSD17B10CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4710507-A | Quinolone inotropic agents | PFIZER INC. (US) | 1987-12-01 | — | — | US | disclosed |
| EP-0148623-A2 | Quinolone inotropic agents | Pfizer Limited (GB) | 1985-07-17 | — | — | EP | disclosed |