Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 1/20 | 0.68 |
| ▸ | CASP2 | P42575 | 1/20 | 0.68 |
| ▸ | USP2 | O75604 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24335266 | 1.00 | CASP3 (0.68) | CASP3CASP2USP2MAPTHPGD | |
| SCHEMBL30516491 | 0.92 | CASP3 (0.72) | CASP3CASP2USP2MAPTHPGD | |
| SCHEMBL24335146 | 0.92 | CASP3 (0.72) | CASP3CASP2USP2MAPTHPGD | |
| SCHEMBL29580313 | 0.88 | CASP3 (0.67) | CASP3CASP2USP2MAPTHPGD | |
| SCHEMBL24335274 | 0.86 | CASP3 (0.72) | CASP3CASP2USP2MAPTHPGD | |
| SCHEMBL29064837 | 0.84 | CASP3 (0.70) | CASP3CASP2USP2MAPTHPGD | |
| SCHEMBL30516492 | 0.84 | CASP3 (0.70) | CASP3CASP2USP2MAPTHPGD | |
| SCHEMBL24335142 | 0.84 | CASP3 (0.66) | CASP3CASP2USP2MAPTHPGD | |
| SCHEMBL25430532 | 0.82 | CASP3 (0.76) | CASP3CASP2ALDH1A1KMT2AKDM4E | |
| SCHEMBL11035331 | 0.81 | CASP3 (1.00) | CASP3CASP2MAPTALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116528867-A | Compounds for the treatment of Alzheimer's disease | 艾伯塔大学理事会 | 2023-08-01 | — | — | CN | disclosed |