Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 11/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | JAK1 | P23458 | 1/20 | 0.36 |
| ▸ | TYK2 | P29597 | 1/20 | 0.36 |
| ▸ | JAK3 | P52333 | 1/20 | 0.36 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MPI | P34949 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 2/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | IDH1 | O75874 | 1/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23853811 | 0.85 | HTR1A (0.40) | P2RX7KDM4EMPIL3MBTL1HTR1A | |
| SCHEMBL22778029 | 0.82 | KDM4E (0.37) | P2RX7KDM4EMPIL3MBTL1HTR1A | |
| SCHEMBL29714391 | 0.82 | KDM4E (0.37) | P2RX7KDM4EMPIL3MBTL1HTR1A | |
| SCHEMBL2563345 | 0.82 | HTR1A (0.38) | P2RX7KDM4EMPIL3MBTL1HTR1A | |
| SCHEMBL29262978 | 0.81 | JAK2 (0.36) | P2RX7JAK2JAK1TYK2JAK3 | |
| SCHEMBL30416757 | 0.81 | OPRL1 (0.49) | P2RX7OPRL1 | |
| SCHEMBL30445559 | 0.79 | IDH1 (0.34) | P2RX7JAK2JAK1TYK2JAK3 | |
| SCHEMBL26152156 | 0.79 | IDH1 (0.34) | P2RX7JAK2JAK1TYK2JAK3 | |
| SCHEMBL30416904 | 0.78 | P2RX7 (0.38) | P2RX7KDM4EL3MBTL1 | |
| SCHEMBL3784551 | 0.77 | HTR1A (0.55) | HTR1ASLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116528862-A | Compounds and compositions for the treatment of diseases associated with STING activity | 艾福姆德尤股份有限公司 | 2023-08-01 | — | — | CN | disclosed |