Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30516637 | 0.81 | NPC1 (0.38) | CNR2NPC1RAB9A | |
| SCHEMBL30516656 | 0.80 | TSHR (0.49) | KMT2ASMN1; SMN2MEN1ALDH1A1NPC1 | |
| SCHEMBL30516667 | 0.77 | HDAC1 (0.40) | PTGDRNPC1RAB9AHPGD | |
| SCHEMBL30516661 | 0.76 | NPC1 (0.42) | KMT2ASMN1; SMN2ALDH1A1MAPTNPC1 | |
| SCHEMBL30516655 | 0.76 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL30516645 | 0.76 | NAMPT (0.39) | CNR2NAMPTPTGDRSMN1; SMN2CRBN | |
| SCHEMBL25607337 | 0.65 | NAMPT (0.48) | NAMPTKMT2ASMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL30516657 | 0.65 | TSHR (0.52) | KMT2AMEN1ALDH1A1NPC1RAB9A | |
| SCHEMBL30135621 | 0.65 | CHRM2 (0.32) | HPGDLMNA | |
| SCHEMBL4774133 | 0.63 | MAPK10 (0.51) | NAMPTKMT2ASMN1; SMN2MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116529238-A | Novel prostaglandin E 2 Compounds with receptor inhibiting activity and uses thereof | 治纳辅医药科技有限公司 | 2023-08-01 | — | — | CN | disclosed |