SCHEMBL30516676

SCHEMBL30516676

COc1ccc(C(O)C2CCN(Cc3ccccc3)CC2)cc1

nearest known ligand 0.72

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 2/20 0.61
MEN1 O00255 1/20 0.57
KMT2A Q03164 1/20 0.57
KDM4E B2RXH2 1/20 0.56
CYP1A2 P05177 1/20 0.56
CYP3A4 P08684 1/20 0.56
CYP2D6 P10635 1/20 0.56
TSHR P16473 1/20 0.56
HTR2A P28223 1/20 0.56
HTR2C P28335 1/20 0.56
ACHE P22303 1/20 0.56
BACE1 P56817 1/20 0.56
CHRM2 P08172 1/20 0.53
CHRM3 P20309 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9329079 0.88 HTR2A (0.76) SIGMAR1KDM4ECYP1A2CYP3A4CYP2D6
Hydrochloric Acid SCHEMBL9649783 0.86 HTR2A (0.74) SIGMAR1KDM4ECYP1A2CYP3A4CYP2D6
SCHEMBL9327531 0.82 HTR2A (0.76) SIGMAR1KDM4ECYP1A2CYP3A4CYP2D6
SCHEMBL10834365 0.82 SIGMAR1 (0.64) SIGMAR1MEN1KMT2AACHEBACE1
SCHEMBL4463896 0.82 KDM4E (0.74) SIGMAR1KDM4E
SCHEMBL9327580 0.81 HTR2A (0.70) SIGMAR1KDM4ECYP1A2CYP3A4CYP2D6
SCHEMBL28171880 0.81 SMN1; SMN2 (0.47) MEN1KMT2AKDM4ECYP1A2CYP3A4
SCHEMBL24359228 0.79 OPRD1 (0.56) MEN1KMT2AKDM4ECYP1A2CYP3A4
SCHEMBL9327527 0.78 OPRM1 (0.50) KDM4ECYP1A2CYP3A4CYP2D6TSHR
SCHEMBL493660 0.78 SIGMAR1 (0.58) SIGMAR1MEN1KMT2AACHEBACE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116529252-A Prodrugs for sustained release of therapeutic agents and uses thereof 重庆两江药物研发中心有限公司 2023-08-01 CN disclosed