Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 5/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | CFTR | P13569 | 3/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | PTGES | O14684 | 1/20 | 0.33 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24478766 | 1.00 | KDM4E (0.41) | KDM4EPOLBGAAHSD17B10ALDH1A1 | |
| SCHEMBL30516694 | 0.85 | KDM4E (0.39) | KDM4EHSD17B10ALDH1A1MAPTTSHR | |
| SCHEMBL24478656 | 0.85 | KDM4E (0.39) | KDM4EHSD17B10ALDH1A1MAPTTSHR | |
| SCHEMBL1004632 | 0.79 | KDM4E (0.58) | KDM4EPOLBGAAHSD17B10ALDH1A1 | |
| SCHEMBL16598552 | 0.78 | ALDH1A1 (0.45) | KDM4EHSD17B10ALDH1A1MAPTTSHR | |
| SCHEMBL27147584 | 0.77 | KDM4E (0.49) | KDM4EPOLBGAAHSD17B10ALDH1A1 | |
| SCHEMBL26604345 | 0.76 | LRRK2 (0.48) | GAAALDH1A1HPGDPTGES | |
| SCHEMBL24478734 | 0.74 | NPC1 (0.38) | KDM4EPOLBHSD17B10ALDH1A1MAPT | |
| SCHEMBL30516692 | 0.74 | NPC1 (0.38) | KDM4EPOLBHSD17B10ALDH1A1MAPT | |
| SCHEMBL31064366 | 0.73 | KDM4E (0.46) | KDM4EPOLBGAAHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116601149-A | Aminoquinazoline derivatives as P2X3 inhibitors | 奇斯药制品公司 | 2023-08-15 | — | — | CN | disclosed |