Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.37 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.37 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CFD | P00746 | 2/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | LCK | P06239 | 1/20 | 0.32 |
| ▸ | FYN | P06241 | 1/20 | 0.32 |
| ▸ | CDC25B | P30305 | 1/20 | 0.32 |
| ▸ | CASP6 | P55212 | 1/20 | 0.32 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.32 |
| ▸ | PTGES | O14684 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24478656 | 1.00 | KDM4E (0.39) | KDM4EGLAAKR1C3AKR1C2AKR1C1 | |
| SCHEMBL24478766 | 0.85 | KDM4E (0.41) | KDM4EGLAHSD17B10TSHRALDH1A1 | |
| SCHEMBL30516698 | 0.85 | KDM4E (0.41) | KDM4EGLAHSD17B10TSHRALDH1A1 | |
| SCHEMBL670605 | 0.78 | ALDH1A1 (0.36) | KDM4EGLAHSD17B10TSHRALDH1A1 | |
| SCHEMBL1319775 | 0.74 | HSD17B10 (0.54) | KDM4EGLAAKR1C3AKR1C2AKR1C1 | |
| Bromide SCHEMBL14358987 | 0.73 | HSD17B10 (0.53) | KDM4EGLAAKR1C3AKR1C2AKR1C1 | |
| SCHEMBL31493053 | 0.73 | TSHR (0.37) | KDM4EHSD17B10TSHRALDH1A1LCK | |
| SCHEMBL30516696 | 0.72 | LDHA (0.42) | LCLAT1 | |
| SCHEMBL24478751 | 0.72 | LDHA (0.42) | LCLAT1 | |
| SCHEMBL20522192 | 0.71 | PKM (0.46) | KDM4ETSHRALDH1A1PKMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116601149-A | Aminoquinazoline derivatives as P2X3 inhibitors | 奇斯药制品公司 | 2023-08-15 | — | — | CN | disclosed |