Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | JAK1 | P23458 | 1/20 | 0.30 |
| ▸ | JAK2 | O60674 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lithium Ion SCHEMBL27038869 | 0.78 | HRH3 (0.37) | HRH3LTA4HKDM4EALDH1A1JAK1 | |
| SCHEMBL27038694 | 0.75 | SMN1; SMN2 (0.41) | HRH3LTA4HALDH1A1 | |
| SCHEMBL28159166 | 0.75 | HRH3 (0.36) | HRH3LTA4HKDM4EALDH1A1 | |
| SCHEMBL18838416 | 0.71 | KMT2A (0.50) | ALDH1A1 | |
| SCHEMBL2477198 | 0.71 | LTA4H (0.36) | HRH3LTA4HKDM4EALDH1A1 | |
| SCHEMBL11411310 | 0.71 | ALDH1A1 (0.38) | LTA4HKDM4EALDH1A1 | |
| SCHEMBL26180864 | 0.70 | HSD17B10 (0.37) | HRH3LTA4H | |
| SCHEMBL16405709 | 0.69 | DPP4 (0.39) | KDM4EALDH1A1JAK1JAK2 | |
| SCHEMBL1010131 | 0.69 | KDM4E (0.40) | HRH3KDM4E | |
| SCHEMBL1006688 | 0.69 | KDM4E (0.40) | HRH3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116669724-A | T-type calcium channel modulators and methods of use thereof | 普拉西斯精密医药公司 | 2023-08-29 | — | — | CN | disclosed |