Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28166706 | 0.88 | L3MBTL3 (0.35) | HRH3LTA4H | |
| SCHEMBL28119684 | 0.76 | CFB (0.30) | — | |
| SCHEMBL27038694 | 0.76 | SMN1; SMN2 (0.41) | HRH3LTA4HALDH1A1 | |
| SCHEMBL2477198 | 0.76 | LTA4H (0.36) | HRH3LTA4HKDM4EALDH1A1 | |
| SCHEMBL10035079 | 0.76 | HRH3 (0.43) | HRH3LTA4HKDM4EALDH1A1 | |
| SCHEMBL11411310 | 0.75 | ALDH1A1 (0.38) | LTA4HKDM4EALDH1A1 | |
| SCHEMBL30516886 | 0.75 | HRH3 (0.37) | HRH3LTA4HKDM4EALDH1A1 | |
| Lithium Ion SCHEMBL27038869 | 0.75 | HRH3 (0.37) | HRH3LTA4HKDM4EALDH1A1 | |
| SCHEMBL1516113 | 0.73 | ACHE (0.45) | HRH3ALDH1A1 | |
| SCHEMBL27650078 | 0.73 | KDM4E (0.37) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105916845-B | N- heteroaryl compound and composition for inhibiting the active N- azaspiro cycloalkanes of SHP2 to replace | 诺华股份有限公司 | 2019-11-12 | — | — | CN | disclosed |
| CN-108659005-A | Quinazoline derivatives as EGFR inhibitors | 南京明德新药研发股份有限公司 | 2018-10-16 | — | — | CN | disclosed |
| CN-108640928-A | Quinazoline compounds as EGFR inhibitor | 南京明德新药研发股份有限公司 | 2018-10-12 | — | — | CN | disclosed |
| CN-108473504-A | Novel dihydropyran hepyramine derivative and application thereof | ST制药株式会社 | 2018-08-31 | — | — | CN | disclosed |
| CN-105593229-B | 1 (β D glycopyranosyls) 1H benzazolyl compounds | 伊莱利利公司 | 2017-07-25 | — | — | CN | disclosed |