SCHEMBL30518181

SCHEMBL30518181

CCc1nc2c(C)cccc2[nH]1

nearest known ligand 0.58

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
DDAH1 O94760 1/20 0.55
MGAM O43451 14/20 0.50
GAA P10253 14/20 0.50
SI P14410 14/20 0.50
MGAM2 Q2M2H8 14/20 0.50
ALDH1A1 P00352 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
ESR1 P03372 1/20 0.47
CBFB Q13951 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4919548 1.00 DDAH1 (0.55) DDAH1MGAMGAASIMGAM2
SCHEMBL4359045 0.87 MGAM (0.51) MGAMGAASIMGAM2ALDH1A1
SCHEMBL1917210 0.86 MGAM (0.47) MGAMGAASIMGAM2ALDH1A1
SCHEMBL4062820 0.84 MGAM (0.51) MGAMGAASIMGAM2ALDH1A1
SCHEMBL7409334 0.84 MGAM (0.49) MGAMGAASIMGAM2ALDH1A1
SCHEMBL4346855 0.84 MGAM (0.51) MGAMGAASIMGAM2ALDH1A1
SCHEMBL18557211 0.83 MGAM (0.45) DDAH1MGAMGAASIMGAM2
SCHEMBL6755252 0.83 MGAM (0.45) MGAMGAASIMGAM2ALDH1A1
Hydrochloric Acid SCHEMBL23497514 0.82 MGAM (0.47) MGAMGAASIMGAM2ALDH1A1
Hydrochloric Acid SCHEMBL7416048 0.82 MGAM (0.47) MGAMGAASIMGAM2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116536228-A Engineering bacterium of 3-methyl-4-nitrobenzoic acid, preparation method and application thereof 迪嘉药业集团股份有限公司 2023-08-04 CN disclosed