Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 14/20 | 0.49 |
| ▸ | GAA | P10253 | 14/20 | 0.49 |
| ▸ | SI | P14410 | 14/20 | 0.49 |
| ▸ | MGAM2 | Q2M2H8 | 14/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | CBFB | Q13951 | 1/20 | 0.46 |
| ▸ | ATP4A | P20648 | 1/20 | 0.45 |
| ▸ | ATP4B | P51164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL23497514 | 0.98 | MGAM (0.47) | MGAMGAASIMGAM2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7416048 | 0.98 | MGAM (0.47) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL4359045 | 0.85 | MGAM (0.51) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL4919548 | 0.84 | DDAH1 (0.55) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL30518181 | 0.84 | DDAH1 (0.55) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL4062820 | 0.82 | MGAM (0.51) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL4346855 | 0.82 | MGAM (0.51) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL10765842 | 0.81 | POLB (0.45) | MGAMGAASIMGAM2ALDH1A1 | |
| Bromide SCHEMBL844133 | 0.81 | MGAM (0.47) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL1917210 | 0.81 | MGAM (0.47) | MGAMGAASIMGAM2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1135374-A1 | BENZIMIDAZOLE COMPOUNDS THAT ARE VITRONECTIN RECEPTOR ANTAGONISTS | SCHERING CORPORATION (US) | 2001-09-26 | — | — | EP | disclosed |
| WO-2000032578-A1 | BENZIMIDAZOLE COMPOUNDS THAT ARE VITRONECTIN RECEPTOR ANTAGONISTS | SCHERING CORPORATION (US) | 2000-06-08 | — | — | WO | disclosed |