Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 7/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 6/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.38 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | CHRNA2 | Q15822 | 3/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25333101 | 1.00 | CHRNB2 (0.39) | CHRNB2CHRNA3MAPTSAE1UBA2 | |
| SCHEMBL25932870 | 0.85 | CHRNB2 (0.38) | CHRNB2CHRNA3MAPTSAE1UBA2 | |
| SCHEMBL13856833 | 0.78 | NPC1 (0.48) | MAPT | |
| SCHEMBL13856839 | 0.77 | KMT2A (0.42) | MAPTGRM5 | |
| SCHEMBL25334094 | 0.72 | RAB9A (0.40) | MAPTSAE1UBA2GRM5 | |
| SCHEMBL2860394 | 0.70 | HPGD (0.44) | CHRNB2CHRNA3HSD11B1 | |
| SCHEMBL15544407 | 0.68 | KCNH2 (0.45) | CHRNB2MAPTSAE1UBA2GRM5 | |
| SCHEMBL7453866 | 0.67 | CYP2A6 (0.41) | — | |
| SCHEMBL17079717 | 0.66 | MAPT (0.58) | MAPTSAE1UBA2FFAR1FFAR4 | |
| SCHEMBL1934205 | 0.66 | KCNH2 (0.42) | CHRNB2CHRNA3MAPTSAE1UBA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4472630-A2 | SELECTIVE AGENTS TARGETING MYCOBACTERIUM TUBERCULOSIS | University of Mississippi (US) | 2024-12-11 | — | — | EP | disclosed |
| WO-2023147571-A2 | SELECTIVE AGENTS TARGETING MYCOBACTERIUM TUBERCULOSIS | UNIVERSITY OF MISSISSIPPI (US) | 2023-08-03 | — | — | WO | disclosed |