Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR3 | P22607 | 2/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | AURKA | O14965 | 2/20 | 0.46 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.46 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | SYK | P43405 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CLK1 | P49759 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24328682 | 1.00 | FGFR3 (0.46) | FGFR3KDRAURKAAURKBCHEK1 | |
| SCHEMBL24328681 | 0.87 | FGFR3 (0.49) | FGFR3KDRAURKAAURKBCHEK1 | |
| SCHEMBL24328711 | 0.87 | CHEK1 (0.52) | FGFR3KDRAURKAAURKBCHEK1 | |
| SCHEMBL24328703 | 0.80 | FGFR3 (0.51) | FGFR3KDRAURKAAURKBCHEK1 | |
| SCHEMBL25406013 | 0.79 | PLA2G2A (0.47) | FGFR3KDRAURKAAURKBCHEK1 | |
| SCHEMBL29498949 | 0.79 | FGFR3 (0.56) | FGFR3KDRAURKAAURKBCHEK1 | |
| SCHEMBL24327350 | 0.79 | FGFR3 (0.56) | FGFR3KDRAURKAAURKBCHEK1 | |
| SCHEMBL28724019 | 0.77 | FGFR3 (0.51) | FGFR3KDRAURKAAURKBCHEK1 | |
| SCHEMBL24327347 | 0.77 | KDR (0.53) | FGFR3KDRAURKAAURKBCHEK1 | |
| SCHEMBL24327827 | 0.77 | FGFR3 (0.53) | FGFR3KDRAURKAAURKBFGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114369097-B | Heteroaromatic AhR inhibitors | 山东轩竹医药科技有限公司 | 2023-07-14 | — | — | CN | disclosed |