Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 4/20 | 0.48 |
| ▸ | KIT | P10721 | 2/20 | 0.46 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 7/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25341619 | 1.00 | KIF11 (0.48) | KIF11KITSLC22A12TRPV1SLC6A2 | |
| SCHEMBL25971711 | 0.87 | KIF11 (0.45) | KIF11SLC22A12TRPV1SLC6A2SLC6A4 | |
| SCHEMBL30482541 | 0.84 | SLC6A2 (0.40) | KIF11SLC22A12TRPV1SLC6A2SLC6A4 | |
| SCHEMBL25377591 | 0.84 | SLC6A2 (0.40) | KIF11SLC22A12TRPV1SLC6A2SLC6A4 | |
| SCHEMBL30519319 | 0.81 | PTGS2 (0.35) | KIF11TRPV1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL25343113 | 0.81 | PTGS2 (0.35) | KIF11TRPV1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL25378744 | 0.80 | SLC22A12 (0.44) | KIF11SLC22A12TRPV1SLC6A2SLC6A4 | |
| SCHEMBL30482544 | 0.80 | SLC22A12 (0.44) | KIF11SLC22A12TRPV1SLC6A2SLC6A4 | |
| SCHEMBL30519311 | 0.79 | SLC6A2 (0.36) | KIF11SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL25341461 | 0.79 | SLC6A2 (0.36) | KIF11SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146513-A1 | COMPOUNDS AND METHODS OF USE THEREOF | VIVACE THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |