Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 3/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.35 |
| ▸ | KIF11 | P52732 | 3/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.34 |
| ▸ | FEN1 | P39748 | 2/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30519319 | 1.00 | PTGS2 (0.35) | PTGS2TRPV1KIF11ALOX5APFEN1 | |
| SCHEMBL30519311 | 0.88 | SLC6A2 (0.36) | PTGS2KIF11ALOX5APFEN1SLC6A2 | |
| SCHEMBL25341461 | 0.88 | SLC6A2 (0.36) | PTGS2KIF11ALOX5APFEN1SLC6A2 | |
| SCHEMBL25975488 | 0.84 | PDE10A (0.35) | TRPV1PDE10AALDH1A1NPC1CASP3 | |
| SCHEMBL30519400 | 0.81 | KIF11 (0.48) | TRPV1KIF11SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL25341619 | 0.81 | KIF11 (0.48) | TRPV1KIF11SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL25971711 | 0.78 | KIF11 (0.45) | TRPV1KIF11ALOX5APFEN1SLC6A2 | |
| SCHEMBL25378347 | 0.77 | LMNA (0.41) | SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL30482519 | 0.77 | LMNA (0.41) | SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL25340813 | 0.77 | KCNH2 (0.38) | TRPV1ALOX5APFEN1LMNAPDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146513-A1 | COMPOUNDS AND METHODS OF USE THEREOF | VIVACE THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |