Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.71 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.71 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.68 |
| ▸ | RAB9A | P51151 | 3/20 | 0.68 |
| ▸ | NPC1 | O15118 | 2/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.68 |
| ▸ | TSHR | P16473 | 2/20 | 0.65 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | CASP3 | P42574 | 1/20 | 0.64 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | MITF | O75030 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5652014 | 0.95 | KMT2A (0.76) | CYP1A2CYP2C9CYP2C19KMT2ASMN1; SMN2 | |
| SCHEMBL830030 | 0.86 | SMN1; SMN2 (0.78) | CYP1A2CYP2C9CYP2C19KMT2ASMN1; SMN2 | |
| SCHEMBL25224294 | 0.84 | ALDH1A1 (0.79) | CYP1A2CYP2C9CYP2C19KMT2ASMN1; SMN2 | |
| SCHEMBL18343856 | 0.84 | ALDH1A1 (0.72) | CYP1A2CYP2C9CYP2C19KMT2ASMN1; SMN2 | |
| SCHEMBL8247308 | 0.83 | CYP1A2 (1.00) | CYP1A2CYP2C9CYP2C19KMT2ASMN1; SMN2 | |
| SCHEMBL19066237 | 0.83 | ALDH1A1 (0.82) | KMT2ASMN1; SMN2RAB9ANPC1TSHR | |
| SCHEMBL5101418 | 0.83 | KMT2A (0.82) | CYP1A2CYP2C9CYP2C19KMT2ASMN1; SMN2 | |
| SCHEMBL4598628 | 0.81 | EPHX1 (0.68) | CYP1A2CYP2C9CYP2C19KMT2ASMN1; SMN2 | |
| SCHEMBL7380436 | 0.81 | CYP1A2 (0.69) | CYP1A2CYP2C9CYP2C19KMT2ASMN1; SMN2 | |
| SCHEMBL5649640 | 0.81 | KMT2A (1.00) | CYP1A2CYP2C9CYP2C19KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11697636-B2 | Substituted benzamides | HOFFMANN-LA ROCHE INC. (US) | 2023-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11697636-B2 | Substituted benzamides | TAAR1, TAAR5, NPY1R | CYP1A2 164/4885CYP2C9 350/4885CYP2C19 265/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.