Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | GLS | O94925 | 1/20 | 0.46 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7514125 | 1.00 | ALDH1A1 (0.57) | ALDH1A1RAB9ANPC1L3MBTL1GAA | |
| SCHEMBL24796112 | 0.98 | ALDH1A1 (0.56) | ALDH1A1RAB9ANPC1L3MBTL1GAA | |
| SCHEMBL5494327 | 0.95 | ALDH1A1 (0.59) | ALDH1A1RAB9ANPC1GAAHPGD | |
| SCHEMBL18071022 | 0.80 | TSHR (0.48) | ALDH1A1RAB9ANPC1L3MBTL1GAA | |
| SCHEMBL29163908 | 0.78 | ALDH1A1 (0.66) | ALDH1A1RAB9AGAAHPGDKMT2A | |
| SCHEMBL30690126 | 0.78 | ALDH1A1 (0.66) | ALDH1A1RAB9AGAAHPGDKMT2A | |
| SCHEMBL6699936 | 0.76 | GLS (0.71) | RAB9ANPC1L3MBTL1SMN1; SMN2GLS | |
| SCHEMBL21384206 | 0.76 | ALDH1A1 (0.52) | ALDH1A1RAB9ANPC1GAAHPGD | |
| SCHEMBL21383938 | 0.76 | ALDH1A1 (0.52) | ALDH1A1RAB9ANPC1GAAHPGD | |
| SCHEMBL3243125 | 0.76 | ALDH1A1 (0.69) | ALDH1A1RAB9AGAAHPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116615251-A | Antibody-drug conjugates comprising GLP1 peptide mimetics and the uses thereof | 瑞泽恩制药公司 | 2023-08-18 | — | — | CN | disclosed |