Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | PER2 | O15055 | 1/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5494327 | 0.85 | ALDH1A1 (0.59) | TSHRSMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL7514125 | 0.80 | ALDH1A1 (0.57) | SMN1; SMN2L3MBTL1ALDH1A1NPC1RAB9A | |
| SCHEMBL30520820 | 0.80 | ALDH1A1 (0.57) | SMN1; SMN2L3MBTL1ALDH1A1NPC1RAB9A | |
| SCHEMBL24796112 | 0.79 | ALDH1A1 (0.56) | SMN1; SMN2L3MBTL1ALDH1A1NPC1RAB9A | |
| SCHEMBL2604740 | 0.74 | CA12 (0.58) | SMN1; SMN2ALDH1A1NPC1RAB9AKMT2A | |
| SCHEMBL4278259 | 0.74 | KMT2A (0.59) | TSHRL3MBTL1ALDH1A1KMT2AMAPK1 | |
| SCHEMBL5420775 | 0.73 | GAA (0.53) | TSHRSMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL7277601 | 0.73 | CA1 (0.68) | TSHRALDH1A1HTTACHEKMT2A | |
| SCHEMBL29619555 | 0.73 | CA1 (0.68) | TSHRALDH1A1HTTACHEKMT2A | |
| SCHEMBL927806 | 0.71 | CA12 (0.54) | SMN1; SMN2ALDH1A1NPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016144797-A1 | ALPHA 7 NICOTINIC ACETYLCHOLINE RECEPTOR ALLOSTERIC MODULATORS, THEIR DERIVATIVES AND USES THEREOF | ALPHARMAGEN, LLC (US) | 2016-09-15 | — | — | WO | disclosed |